The Paradox of Progress: Environmental Disruption of Metabolism and the Diabetes Epidemic

被引:171
作者
Neel, Brian A. [1 ]
Sargis, Robert M. [1 ]
机构
[1] Univ Chicago, Dept Med, Kovler Diabet Ctr,Comm Mol Metab & Nutr, Inst Endocrine Discovery & Clin Care, Chicago, IL 60637 USA
基金
美国国家卫生研究院;
关键词
PERSISTENT ORGANIC POLLUTANTS; ENDOCRINE DISRUPTORS; BISPHENOL-A; POLYCHLORINATED-BIPHENYLS; GLUCOSE-HOMEOSTASIS; INSULIN-RESISTANCE; NATIONAL-HEALTH; DIOXIN EXPOSURE; US POPULATION; PREVALENCE;
D O I
10.2337/db11-0153
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:1838 / 1848
页数:11
相关论文
共 74 条
  • [51] Arsenic induces pancreatic β-cell apoptosis via the oxidative stress-regulated mitochondria-dependent and endoplasmic reticulum stress-triggered signaling pathways
    Lu, Tien-Hui
    Su, Chin-Chuan
    Chen, Ya-Wen
    Yang, Ching-Yao
    Wu, Chin-Ching
    Hung, Dong-Zong
    Chen, Chun-Hung
    Cheng, Po-Wen
    Liu, Shing-Hwa
    Huang, Chun-Fa
    [J]. TOXICOLOGY LETTERS, 2011, 201 (01) : 15 - 26
  • [52] Xenoreceptors CAR and PXR activation and consequences on lipid metabolism, glucose homeostasis, and inflammatory response
    Moreau, Amelie
    Vilarem, Marie Jose
    Maurel, Patrick
    Pascussi, Jean Marc
    [J]. MOLECULAR PHARMACEUTICS, 2008, 5 (01) : 35 - 41
  • [53] 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Impairs an Insulin Signaling Pathway through the Induction of Tumor Necrosis Factor-α in Adipocytes
    Nishiumi, Shin
    Yoshida, Masaru
    Azuma, Takeshi
    Yoshida, Ken-ichi
    Ashida, Hitoshi
    [J]. TOXICOLOGICAL SCIENCES, 2010, 115 (02) : 482 - 491
  • [54] Economic costs of diabetes in the US in 2007
    Petersen, Matt
    [J]. DIABETES CARE, 2008, 31 (03) : 596 - 615
  • [55] Quintero-Somaini Adriana., 2004, HIDDEN DANGER ENV HL
  • [56] Oxidative stress, insulin signaling, and diabetes
    Rains, Justin L.
    Jain, Sushil K.
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 2011, 50 (05) : 567 - 575
  • [57] Linking dioxins to diabetes: Epidemiology and biologic plausibility
    Remillard, RBJ
    Bunce, NJ
    [J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 2002, 110 (09) : 853 - 858
  • [58] Persistent Organic Pollutant Exposure Leads to Insulin Resistance Syndrome
    Ruzzin, Jerome
    Petersen, Rasmus
    Meugnier, Emmanuelle
    Madsen, Lise
    Lock, Erik-Jan
    Lillefosse, Haldis
    Ma, Tao
    Pesenti, Sandra
    Sonne, Si Brask
    Marstrand, Troels Torben
    Malde, Marian Kjellevold
    Du, Zhen-Yu
    Chavey, Carine
    Fajas, Lluis
    Lundebye, Anne-Katrine
    Brand, Christian Lehn
    Vidal, Hubert
    Kristiansen, Karsten
    Froyland, Liver
    [J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 2010, 118 (04) : 465 - 471
  • [59] Environmental Endocrine Disruptors Promote Adipogenesis in the 3T3-L1 Cell Line through Glucocorticoid Receptor Activation
    Sargis, Robert M.
    Johnson, Daniel N.
    Choudhury, Rashikh A.
    Brady, Matthew J.
    [J]. OBESITY, 2010, 18 (07) : 1283 - 1288
  • [60] Low-dose dioxins alter gene expression related to cholesterol biosynthesis, lipogenesis, and glucose metabolism through the aryl hydrocarbon receptor-mediated pathway in mouse liver
    Sato, Shoko
    Shirakawa, Hitoshi
    Tomita, Shuhei
    Ohsaki, Yusuke
    Haketa, Keiichi
    Tooi, Osamu
    Santo, Noriaki
    Tohkin, Masahiro
    Furukawa, Yuji
    Gonzalez, Frank J.
    Komai, Michio
    [J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 2008, 229 (01) : 10 - 19