Pathologic aspects of AIDS malignancies

被引：27
作者：
Bellan, C [1 ]
De Falco, G [1 ]
Lazzi, S [1 ]
Leoncini, L [1 ]
机构：
[1] Univ Siena, Dept Human Pathol & Oncol, Nuovo Policlin Le Scotte, I-53100 Siena, Italy
来源：
ONCOGENE | 2003年 / 22卷 / 42期
关键词：
AIDS; HIV; neoplasm; pathology;
D O I：
10.1038/sj.onc.1206815
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Since the emergence of the HIV pandemic, a close association between HIV infection and the development of a selected group of cancers has been acknowledged. The introduction of highly active antiretroviral therapy, however, has had a dramatic impact on the incidences of several AIDS-defining malignancies. This suggests the possibility of a direct and indirect role of HIV in HIV-related tumor genesis. The aim of this paper is to review the pathology of AIDS-related malignancies, taking into account the pathogenetic mechanisms and their potential for improving the treatment of these tumors.
引用
收藏
页码：6639 / 6645
页数：7
相关论文
共 77 条
  • [1] ANGIOGENIC PROPERTIES OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 TAT PROTEIN
    ALBINI, A
    BARILLARI, G
    BENELLI, R
    GALLO, RC
    ENSOLI, B
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (11) : 4838 - 4842
  • [2] Morphological, histochemical, immunohistochemical, and ultrastructural characterization of tumors and dysplastic and non-neoplastic lesions arising in BK virus/tat transgenic mice
    Altavilla, G
    Trabanelli, C
    Merlin, M
    Caputo, A
    Lanfredi, M
    Barbanti-Brodano, G
    Corallini, A
    [J]. AMERICAN JOURNAL OF PATHOLOGY, 1999, 154 (04) : 1231 - 1244
  • [3] Epstein-Barr virus associated lymphoproliferations in the AIDS setting
    Ambinder, RF
    [J]. EUROPEAN JOURNAL OF CANCER, 2001, 37 (10) : 1209 - 1216
  • [4] Physical and functional interaction of HIV-1 tat with E2F-4, a transcriptional regulator of mammalian cell cycle
    Ambrosino, C
    Palmieri, C
    Puca, A
    Trimboli, F
    Schiavone, M
    Olimpico, F
    Ruocco, MR
    di Leva, F
    Toriello, M
    Quinto, I
    Venuta, S
    Scala, G
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (35) : 31448 - 31458
  • [5] Tonsillar memory B cells, latently infected with Epstein-Barr virus, express the restricted pattern of latent genes previously found only in Epstein-Barr virus-associated tumors
    Babcock, GJ
    Thorley-Lawson, DA
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (22) : 12250 - 12255
  • [6] Angiogenic effects of extracellular human immunodeficiency virus type 1 Tat protein and its role in the pathogenesis of AIDS-associated Kaposi's sarcoma
    Barillari, G
    Ensoli, B
    [J]. CLINICAL MICROBIOLOGY REVIEWS, 2002, 15 (02) : 310 - +
  • [7] MICROSATELLITE INSTABILITY IN PRIMARY NEOPLASMS FROM HIV+ PATIENTS
    BEDI, GC
    WESTRA, WH
    FARZADEGAN, H
    PITHA, PM
    SIDRANSKY, D
    [J]. NATURE MEDICINE, 1995, 1 (01) : 65 - 68
  • [8] KAPOSIS SARCOMA AMONG PERSONS WITH AIDS - A SEXUALLY-TRANSMITTED INFECTION
    BERAL, V
    PETERMAN, TA
    BERKELMAN, RL
    JAFFE, HW
    [J]. LANCET, 1990, 335 (8682) : 123 - 128
  • [9] Intra-epithelial and invasive cervical neoplasia during HIV infection
    Boccalon, M
    Tirelli, U
    Sopracordevole, F
    Vaccher, E
    [J]. EUROPEAN JOURNAL OF CANCER, 1996, 32A (13) : 2212 - 2217
  • [10] Aids-related malignancies
    Boshoff, C
    Weiss, R
    [J]. NATURE REVIEWS CANCER, 2002, 2 (05) : 373 - 382
12345678