Pathologic aspects of AIDS malignancies

被引：27

作者：

Bellan, C ^{[1
]}

De Falco, G ^{[1
]}

Lazzi, S ^{[1
]}

Leoncini, L ^{[1
]}

机构：

[1] Univ Siena, Dept Human Pathol & Oncol, Nuovo Policlin Le Scotte, I-53100 Siena, Italy

来源：

ONCOGENE | 2003年 / 22卷 / 42期

关键词：

AIDS; HIV; neoplasm; pathology;

D O I：

10.1038/sj.onc.1206815

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Since the emergence of the HIV pandemic, a close association between HIV infection and the development of a selected group of cancers has been acknowledged. The introduction of highly active antiretroviral therapy, however, has had a dramatic impact on the incidences of several AIDS-defining malignancies. This suggests the possibility of a direct and indirect role of HIV in HIV-related tumor genesis. The aim of this paper is to review the pathology of AIDS-related malignancies, taking into account the pathogenetic mechanisms and their potential for improving the treatment of these tumors.

引用

页码：6639 / 6645

页数：7

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