Nucleic acid isothermal amplification-based soft nanoarchitectonics as an emerging electrochemical biosensing platform

被引:22
作者
Liu, Jing [1 ]
Wang, Ruke [1 ]
Zhou, Hong [2 ,3 ]
Mathesh, Motilal [4 ]
Dubey, Mukul [5 ]
Zhang, Wengan [1 ]
Wang, Bo [1 ]
Yang, Wenrong [4 ]
机构
[1] Shandong Univ Sci & Technol, Coll Chem & Biol Engn, Qingdao 266590, Peoples R China
[2] Qingdao Univ Sci & Technol, Shandong Key Lab Biochem Anal, Qingdao 266042, Peoples R China
[3] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China
[4] Deakin Univ, Sch Life & Environm Sci, Geelong, Vic 3217, Australia
[5] TERI Gram, TERI Deakin Nanobiotechnol Ctr, Gurugram, Haryana, India
基金
中国国家自然科学基金;
关键词
RESONANCE ENERGY-TRANSFER; ELECTROCHEMILUMINESCENCE BIOSENSOR; SIGNAL AMPLIFICATION; ELECTROGENERATED CHEMILUMINESCENCE; CIRCLE AMPLIFICATION; QUANTUM DOTS; LABEL-FREE; DNA; GRAPHENE; STRATEGY;
D O I
10.1039/d2nr02031a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The emergence of nucleic acid isothermal amplification strategies based on soft nanoarchitectonics offers a new dimension to the traditional electrochemical technique, particularly because of its flexibility, high efficiency, and increased sensitivity for analytical applications. Various DNA/RNA isothermal amplification strategies have been developed for the design and fabrication of new electrochemical biosensors for efficient and important biomolecular detection. Herein, we provide an overview of recent efforts in this research field and the strategies for signal-amplified sensing systems, with their biological applications, current challenges and prospects in this promising new area.
引用
收藏
页码:10286 / 10298
页数:13
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