Green synthesis and biological evaluation of some novel azoles as antimicrobial agents

被引：47
|
作者：
Shelke, Sharad [1 ]
Mhaske, Ganesh [1 ]
Gadakh, Sunil [1 ]
Gill, Charnsingh [2 ]
机构：
[1] SSGM Coll, Dept Chem, Kopargaon 423601, MH, India
[2] Dr BAM Univ, Dept Chem, Aurangabad 423601, MH, India
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2010年 / 20卷 / 24期
关键词：
Ultrasound irradiation; Microwave-assisted synthesis; Triazole; Thiadiazole; Antifungal activity; MURINE MODEL; PHARMACODYNAMICS; CONDENSATION; IRRADIATION; INHIBITORS; TRIAZOLE;
D O I：
10.1016/j.bmcl.2010.10.111
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A series of novel fluorine-containing triazoles 3, thiadiazoles 4, and oxadiazoles 5 were synthesized from thiosemicarbazides 2. These reactions were carried out by green technique such as ultrasonication and microwave. All products have been characterized by IR, H-1 NMR, and Mass spectral study and screened for their antimicrobial activity. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：7200 / 7204
页数：5
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