Blastic NK-cell lymphomas (agranular CD4+CD56+hematodermic neoplasms) - A review

被引：206

作者：

Petrella, T

Bagot, M

Willernze, R

Beylot-Barry, M

Vergier, B

Delaunay, M

Meijer, CJLM

Courville, P

Joly, P

Grange, F

De Muret, A

Machet, L

Dompmartin, A

Bosq, J

Durlach, A

Bernard, P

Dalac, S

Dechelotte, P

D'Incan, M

Wechsler, J

Teitell, MA

机构：

[1] Ctr Pathol, F-21000 Dijon, France

[2] CHU Dijon, Dept Pathol, Dijon, France

[3] Hop Henri Mondor, Dept Dermatol, F-94010 Creteil, France

[4] Hop Henri Mondor, Dept Pathol, Creteil, France

[5] Leiden Univ, Dept Dermatol, Ctr Med, Leiden, Netherlands

[6] Haut Leveque Hosp, Dept Dermatol, Pessac, France

[7] Haut Leveque Hosp, Dept Pathol, Pessac, France

[8] St Andre Hosp, Dept Dermatol Cancerol, Bordeaux, France

[9] Vrije Univ Amsterdam, Ctr Med, Dept Pathol, Amsterdam, Netherlands

[10] Hop Charles Nicolle, Dept Pathol, Rouen, France

[11] Hop Charles Nicolle, Dept Dermatol, Rouen, France

[12] Pasteur Hosp, Dept Dermatol, Colmar, France

[13] Trousseau Hosp, Dept Pathol, Tours, France

[14] Trousseau Hosp, Dept Dermatol, Tours, France

[15] Clemenceau Hosp, Dept Dermatol, Caen, France

[16] Inst Gustave Roussy, Dept Pathol, Villejuif, France

[17] Maison Blanche Hosp, Dept Pathol, Reims, France

[18] Bocage Hosp, Dept Dermatol, Dijon, France

[19] Hop Hotel Dieu, Dept Pathol, Clermont Ferrand, France

[20] Hop Hotel Dieu, Dept Dermatol, Clermont Ferrand, France

[21] Univ Calif Los Angeles, David Geffen Sch Med, Jonsson Comprehens Canc Ctr, Dept Pathol, Los Angeles, CA USA

[22] Univ Calif Los Angeles, David Geffen Sch Med, Jonsson Comprehens Canc Ctr, Dept Pediat, Los Angeles, CA USA

来源：

AMERICAN JOURNAL OF CLINICAL PATHOLOGY | 2005年 / 123卷 / 05期

关键词：

CD4; CD56; blastic NK cell;

D O I：

10.1309/GJWNPD8HU5MAJ837

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Blastic natural killer (NK) cell lymphoma (also termed CD4+CD56+ hematodermic neoplasm) is a recently described entity, with the first case reported in 1994. It was suggested initially that the disease originates from NK cells. Since 1994, single cases and a few small series have been published. In this review, data from the literature and a series of 30 cases from the French and Dutch study groups on cutaneous lymphomas are discussed. The major clinical, histopathologic, and phenotypic aspects of the disease and diagnostic criteria and data suggesting a plasmacytoid dendritic cell origin for the tumor cells are provided.

引用

页码：662 / 675

页数：14

共 89 条

[1] HIGH EXPRESSION OF CD56 (N-CAM) IN A PATIENT WITH CUTANEOUS CD4-POSITIVE LYMPHOMA [J].