tert-Butyl 6-amino-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate

被引:0
作者
Gu, Xiao-Bo [1 ]
Jiang, Meng-Jun [1 ]
Cai, Gang-Ming [1 ]
Zhou, Yao-Yuan [1 ]
机构
[1] Jiangsu Inst Nucl Med, Key Lab Nucl Med, Minist Hlth, Jiangsu Key Lab Mol Nucl Med, Wuxi 214063, Peoples R China
来源
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2010年 / 66卷
关键词
ACETONITRILE SOLVATE;
D O I
10.1107/S160053681004777X
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
The title molecule, C13H18N2O3, contains a benzene ring fused to an oxazine ring and one tert-butoxycarbonyl group bound to the N atom of the oxazine ring. Aweak intramolecular C-H center dot center dot center dot O interaction occurs. In the crystal, intermolecular N-H center dot center dot center dot O and C-H center dot center dot center dot O hydrogen bonds stack the molecules down the b axis. Weak C-H center dot center dot center dot N contacts connect the stacks, generating a three-dimensional network.
引用
收藏
页码:O3269 / U1536
页数:9
相关论文
共 8 条
[1]   Straightforward synthesis of 2-substituted 3,4-dihydro-2H-1,4-benzoxazines under solid-liquid phase transfer catalysis conditions [J].
Albanese, D ;
Landini, D ;
Lupi, V ;
Penso, M .
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2003, 42 (04) :680-686
[2]  
[Anonymous], 2008, CRYSTALCLEAR
[3]   (2,2′-bipyridine-κ2N,N′)tricarbonyl(acetonitrile-κN)rhenium(I) hexafluoroantimonate dichloromethane hemisolvate [J].
Chen, YD ;
Zhang, LY ;
Chen, ZN .
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2003, 59 :M429-M430
[4]   Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis [J].
La, Daniel S. ;
Belzile, Julie ;
Bready, James V. ;
Coxon, Angela ;
DeMelfi, Thomas ;
Doerr, Nicholas ;
Estrada, Juan ;
Flynn, Julie C. ;
Flynn, Shaun R. ;
Graceffa, Russell F. ;
Harriman, Shawn P. ;
Larrow, Jay F. ;
Long, Alexander. M. ;
Martin, Matthew W. ;
Morrison, Michael J. ;
Patel, Vinod F. ;
Roveto, Philip M. ;
Wang, Ling ;
Weiss, Matthew M. ;
Whittington, Douglas A. ;
Teffera, Yohannes ;
Zhao, Zhiyang ;
Polverino, Anthony J. ;
Harmanget, Jean-Christophe .
JOURNAL OF MEDICINAL CHEMISTRY, 2008, 51 (06) :1695-1705
[5]  
McCormick K. D., 2008, [No title captured], Patent No. [PCT/US2008/001776, 2008001776]
[6]   Dichloro{N-(2,6-diisopropylphenyl)-2-[(di-2-pyridylmethyl)aminolethanamido}iron(II) acetonitrile solvate [J].
Olmstead, MM ;
Troeltzsch, C ;
Patten, TE .
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2003, 59 :M502-M503
[7]   A short history of SHELX [J].
Sheldrick, George M. .
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2008, 64 :112-122
[8]   1,8-Bis(dimethylamino)naphthalene bis[6-fluoro-2-(trifluoromethyl)-4quinolinol] acetonitrile solvate [J].
Vergeer, P ;
Kooijman, H ;
Schreurs, AMM ;
Kroon, J ;
Grech, E .
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1999, 55 :1822-1824