Roles and controls of mTOR in the heart. Focus on "mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy"

被引：2
作者：
Davis, Paul J. [1 ,2 ,3 ]
Davis, Faith B. [1 ]
Lin, Hung-Yun [1 ]
机构：
[1] Ordway Res Inst, Albany, NY 12208 USA
[2] Albany Med Coll, Albany, NY 12208 USA
[3] Albany Coll Pharm, Albany, NY USA
来源：
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY | 2010年 / 299卷 / 06期
关键词：
MAMMALIAN TARGET; STIMULATION; FAILURE;
D O I：
10.1152/ajpcell.00410.2010
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
引用
收藏
页码：C1250 / C1252
页数：3
相关论文
共 27 条
  • [1] Testosterone induces cardiomyocyte hypertrophy through mammalian target of rapamycin complex 1 pathway
    Altamirano, Francisco
    Oyarce, Cesar
    Silva, Patricio
    Toyos, Marcela
    Wilson, Carlos
    Lavandero, Sergio
    Uhlen, Per
    Estrada, Manuel
    [J]. JOURNAL OF ENDOCRINOLOGY, 2009, 202 (02) : 299 - 307
  • [2] Short term triiodo-L-thyronine treatment inhibits cardiac myocyte apoptosis in border area after myocardial infarction in rats
    Chen, Yue-Feng
    Kobayashi, Satoru
    Chen, Jinghai
    Redetzke, Rebecca A.
    Said, Suleman
    Liang, Qiangrong
    Gerdes, A. Martin
    [J]. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2008, 44 (01) : 180 - 187
  • [3] Noradrenaline enhances the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of PI3K/Akt and the mTOR/S6K pathway
    Chenal, Julie
    Pellerin, Luc
    [J]. JOURNAL OF NEUROCHEMISTRY, 2007, 102 (02) : 389 - 397
  • [4] Molecular Aspects of Thyroid Hormone Actions
    Cheng, Sheue-Yann
    Leonard, Jack L.
    Davis, Paul J.
    [J]. ENDOCRINE REVIEWS, 2010, 31 (02) : 139 - 170
  • [5] Inhibition of mTOR reduces chronic pressure-overload cardiac hypertrophy and fibrosis
    Gao, Xiao-Ming
    Wong, Geoffrey
    Wang, Binghui
    Kiriazis, Helen
    Moore, Xiao-Lei
    Su, Yi-Dan
    Dart, Anthony
    Du, Xiao-Jun
    [J]. JOURNAL OF HYPERTENSION, 2006, 24 (08) : 1663 - 1670
  • [6] GRANVILLE CA, CLIN CANC RES, V12, P679
  • [7] Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway
    Gurusamy, Narasimman
    Lekli, Istvan
    Mukherjee, Subhendu
    Ray, Diptarka
    Ahsan, Md. Kaimul
    Gherghiceanu, Mihaela
    Popescu, Lawrence M.
    Das, Dipak K.
    [J]. CARDIOVASCULAR RESEARCH, 2010, 86 (01) : 103 - 112
  • [8] Pressure-Mediated Hypertrophy and Mechanical Stretch Induces IL-1 Release and Subsequent IGF-1 Generation to Maintain Compensative Hypertrophy by Affecting Akt and JNK Pathways
    Honsho, Shoken
    Nishikawa, Susumu
    Amano, Katsuya
    Zen, Kan
    Adachi, Yasushi
    Kishita, Eigo
    Matsui, Akihiro
    Katsume, Asako
    Yamaguchi, Shinichiro
    Nishikawa, Kenichiro
    Isoda, Kikuo
    Riches, David W. H.
    Matoba, Satoaki
    Okigaki, Mitsuhiko
    Matsubara, Hiroaki
    [J]. CIRCULATION RESEARCH, 2009, 105 (11) : 1149 - U265
  • [9] Thyroid hormone stimulates protein synthesis in the cardiomyocyte by activating the Akt-mTOR and p70S6K pathways
    Kenessey, Agnes
    Ojamaa, Kaie
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (30) : 20666 - 20672
  • [10] Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-γ is regulated by mammalian target of rapamycin
    Kristof, AS
    Marks-Konczalik, J
    Billings, E
    Moss, J
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (36) : 33637 - 33644
123