Electrocatalytic Oxidation and Determination of Rutin by Novel Flowerlike Nano-Co3O4 Particles Modified Glassy Carbon Electrode

A novel flowerlike nano-Co3O4 particles modified glass carbon electrode (F-Co3O4-np/GC/CME) was fabricated by dropwise method. The SEM imagines showed the nano-Co3O4 particles were aggregated into porous form and the XRD spectrum indicated that the nano-Co3O4 particle had pure cubic phase spinel structure. The electrochemical behaviors and kinetic parameters of rutin on F-Co3O4-np/GC/CME were investigated by cyclic voltammetry (CV), chronocoulometry (CC) and semi-derivative voltammetry (SDV). The experimental results showed that the redox peak currents of rutin increased significantly at CME in comparison with those at GCE. The influence of potential scan rate (v) on i(pa) of rutin at CME was studied and the results indicated that the electrode reaction was adsorptive controlled process. In B-R buffer solution, the oxidation peak currents are proportional to the concentrations of rutin over the range from 1. 0 x 10(6) to 4. 5 x 10(4) mol/L and the detection limit is 5. 0 x 10(7) mol/L. This method has been applied to the determination of rutin in four kinds of Chinese herb medicine extractive samples, the recovery is from 99. 5% to 100. 9% and RSD is from 1 7% to 4.5%.