Confirmation of the association between male pattern baldness and the androgen receptor gene

被引:1
|
作者
Levy-Nissenbaum, E
Bar-Natan, M
Frydman, M
Pras, E [1 ]
机构
[1] Chaim Sheba Med Ctr, Danek Gartner Inst Human Genet, IL-52621 Tel Hashomer, Israel
[2] Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel
关键词
male pattern baldness; androgen receptor; single nucleotide polymorphism;
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Male pattern baldness (MPB) is a common phenomenon with a complex mode of inheritance. A recent report has implicated the androgen receptor gene in MPB, but this result has not been confirmed. We analyzed a silent polymorphism in the androgen receptor gene (AR) in a group of 41 bald males and 39 non-bald males, and found a significant association (p < 0.0026), thus confirming the previously reported association between MPB and the AR gene.
引用
收藏
页码:339 / 340
页数:2
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