Confirmation of the association between male pattern baldness and the androgen receptor gene

被引：1

作者：

Levy-Nissenbaum, E

Bar-Natan, M

Frydman, M

Pras, E ^{[1
]}

机构：

[1] Chaim Sheba Med Ctr, Danek Gartner Inst Human Genet, IL-52621 Tel Hashomer, Israel

[2] Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel

来源：

EUROPEAN JOURNAL OF DERMATOLOGY | 2005年 / 15卷 / 05期

关键词：

male pattern baldness; androgen receptor; single nucleotide polymorphism;

D O I：

暂无

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Male pattern baldness (MPB) is a common phenomenon with a complex mode of inheritance. A recent report has implicated the androgen receptor gene in MPB, but this result has not been confirmed. We analyzed a silent polymorphism in the androgen receptor gene (AR) in a group of 41 bald males and 39 non-bald males, and found a significant association (p < 0.0026), thus confirming the previously reported association between MPB and the AR gene.

引用

页码：339 / 340

页数：2

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