Why nonlinear Raman microspectroscopy is more than just a gimmick?

被引：0
作者：
Shutov, Anton [2 ]
Petrov, Georgi, I [1 ]
Zhang, Delong [4 ]
Yakovlev, Vladislav V. [1 ,2 ,3 ]
机构：
[1] Texas A&M Univ, Dept Biomed Engn, College Stn, TX 77843 USA
[2] Texas A&M Univ, Dept Phys & Astron, College Stn, TX 77843 USA
[3] Texas A&M Univ, Dept Elect & Comp Engn, College Stn, TX 77843 USA
[4] Zhejiang Univ, Dept Phys, Hangzhou 310027, Zhejiang, Peoples R China
来源：
LABEL-FREE BIOMEDICAL IMAGING AND SENSING (LBIS) 2020 | 2020年 / 11251卷
基金：
中国国家自然科学基金; 美国国家卫生研究院; 美国国家科学基金会;
关键词：
Raman spectroscopy; microscopy; imaging; dynamics; biomedical; coherent Raman spectroscopy; COHERENT; SCATTERING; INSTRUMENTATION; ENHANCEMENT; PULSES;
D O I：
10.1117/12.2547179
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Coherent Raman microspectroscopy utilizing either stimulated Raman scattering or coherent Raman scattering is gaining popularity in the field of biological imaging. It is generally assumed that coherent Raman spectroscopy provides a stronger signal than conventional spectroscopy based on spontaneous scattering, allowing much faster imaging. In this report we examine non-trivial advantages of coherent Raman microspectroscopy, which haven't been given significant attention lately. In particular, we demonstrate the potential of improving sensitivity of Raman spectroscopy and ability to sense the local nanoenvironment.
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页数：6
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