A novel pyrene based highly selective reversible fluorescent-colorimetric sensor for the rapid detection of Cu2+ ions: application in bio-imaging

被引：41

作者：

Ghorai, Anupam ^{[1
]}

Mondal, Jahangir ^{[1
]}

Manna, Amit Kumar ^{[1
]}

Chowdhury, Shubhamoy ^{[2
]}

Patra, Goutam K. ^{[1
]}

机构：

[1] Guru Ghasidas Vishwavidyalaya, Dept Chem, Bilaspur, CG, India

[2] Univ Gour Banga, Dept Chem, Malda 732103, W Bengal, India

来源：

ANALYTICAL METHODS | 2018年 / 10卷 / 09期

关键词：

MOLECULAR-ORBITAL METHODS; RATIOMETRIC FLUORESCENT; METAL-IONS; BASIS-SETS; COPPER; CU(II); PROBES; CHEMOSENSOR; CADMIUM; CRYSTAL;

D O I：

10.1039/c8ay00097b

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel pyrene derivative containing a benzilmonohydrazone moiety has been prepared following a facile synthetic procedure and exploited for the selective detection of Cu2+ under four different channels (colorimetric, absorption, emission and bio-imaging). In the presence of Cu2+, the chemosensor L provided a significant fluorescence enhancement with an easily detectable colour change from yellow to colourless, whereas other metal ions produced only minor changes in colour or fluorescence intensity. The sensitivity of the fluorescence based assay is 7.8 nM for Cu2+, which is far below the limit mentioned in the World Health Organization (WHO) guidelines for drinking water. H-1 NMR data, the Job plot and the ESI-MS spectrum prove 1:1 stoichiometric complexation between L and Cu2+. The sensing behaviour of the probe has also been well supported by DFT studies. Receptor L exhibits remarkable detection ability in a wide pH range of 4-11 and is successfully utilised in the determination of Cu2+ in real samples. Moreover, L shows its application potential in the detection of Cu2+ in living cells.

引用

页码：1063 / 1073

页数：11

共 71 条

[1] Selective colorimetric and fluorometric sensing of Cu(II) by iminocoumarin derivative in aqueous buffer
Ahamed, B. Nisar
Ghosh, Pradyut
[J]. DALTON TRANSACTIONS, 2011, 40 (24) : 6411 - 6419
[2] [Anonymous], 1998, SMART SAINT REL 5 0
[3] Perspectives in inorganic structural genomics: A trafficking route for copper
Arnesano, F
Banci, L
Bertini, I
Ciofi-Baffoni, S
[J]. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2004, (08) : 1583 - 1593
[4] Photophysical and transition-metal ion signaling behavior of a three-component system comprising a cryptand moiety as the receptor
Banthia, S
Samanta, A
[J]. JOURNAL OF PHYSICAL CHEMISTRY B, 2002, 106 (21) : 5572 - 5577
[5] Neurodegenerative diseases and oxidative stress
Barnham, KJ
Masters, CL
Bush, AI
[J]. NATURE REVIEWS DRUG DISCOVERY, 2004, 3 (03) : 205 - 214
[6] Quantum calculation of molecular energies and energy gradients in solution by a conductor solvent model
Barone, V
Cossi, M
[J]. JOURNAL OF PHYSICAL CHEMISTRY A, 1998, 102 (11) : 1995 - 2001
[7] Crystal and molecular structures of eight-coordinate (CuN4O4) and six-coordinate (CuN4O2) Cu(II) complexes with 4-methyl-5-imidazole-carboxaldehyde or 1-benzyl-2-hydroxymethylimidazole, respectively -: Spectroscopic and potentiometric studies
Barszcz, B
Glowiak, T
Jezierska, J
[J]. POLYHEDRON, 1999, 18 (27) : 3713 - 3721
[8] DENSITY-FUNCTIONAL THERMOCHEMISTRY .3. THE ROLE OF EXACT EXCHANGE
BECKE, AD
[J]. JOURNAL OF CHEMICAL PHYSICS, 1993, 98 (07) : 5648 - 5652
[9] Quantitative imaging of selenium, copper, and zinc in thin sections of biological tissues (Slugs-Genus arion) measured by laser ablation inductively coupled of plasma mass spectrometry
Becker, J. S.
Matusch, A.
Depboylu, C.
Dobrowolska, J.
Zoriy, M. V.
[J]. ANALYTICAL CHEMISTRY, 2007, 79 (16) : 6074 - 6080
[10] Copper and prion disease
Brown, DR
[J]. BRAIN RESEARCH BULLETIN, 2001, 55 (02) : 165 - 173

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