Multicomponent reactions of ammonium thiocyanate, acyl chlorides, alkyl bromides, and enaminones: A facile one-pot synthesis of thiophenes

被引：13

作者：

Hossaini, Zinatossadat ^{[1
]}

Rostami-Charati, Faramarz ^{[2
]}

Soltani, Samira ^{[1
]}

Mirzaei, Anwar ^{[3
]}

Berijani, Kayhaneh ^{[1
]}

机构：

[1] Islamic Azad Univ, Dept Chem, Qaemshahr Branch, Qaemshahr, Iran

[2] Gonbad Kavous Univ, Dept Chem, Fac Sci, Gonbad, Iran

[3] Islamic Azad Univ, Dept Chem, Sanandaj Branch, Sanandaj, Iran

来源：

MOLECULAR DIVERSITY | 2011年 / 15卷 / 04期

关键词：

Thiophene; Ammonium thiocyanate; Carbonyl compounds; Solvent-free conditions; SUBSTITUTED THIOPHENES;

D O I：

10.1007/s11030-011-9322-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An efficient synthesis of thiophene derivatives is described via one-pot reaction between ammonium thiocyanate, acyl chlorides, alpha-halocarbonyls, and enaminones under solvent-free conditions at 65 degrees C. The mild reaction conditions and high yields of the products exhibit the good synthetic advantage of these methods.

引用

页码：911 / 916

页数：6