COVID-19: a hypothesis regarding the ventilation-perfusion mismatch

被引：71

作者：

Santamarina, Mario G. ^{[1
,2
]}

Boisier, Dominique ^{[3
]}

Contreras, Roberto ^{[4
]}

Baque, Martiniano ^{[5
]}

Volpacchio, Mariano ^{[6
]}

Beddings, Ignacio ^{[7
]}

机构：

[1] Hosp Naval Almirante Nef, Radiol Dept, Subida Alessandri S-N, Vina Del Mar, Chile

[2] Hosp Dr Eduardo Pereira, Radiol Dept, Enrique Ibsen S-N, Valparaiso, Chile

[3] Hosp Naval Almirante Nef, Intens Care Unit, Subida Alessandri S-N, Vina Del Mar, Chile

[4] Hosp San Martin Quillota, Intens Care Unit, La Concepcion 1050, Quillota, Chile

[5] Hosp IESS Los Ceibos, Intens Care Unit, Av El Bombero Km 6-5, Guayaquil, Ecuador

[6] Ctr Diagnost Dr Enrique Rossi, Radiol Dept, RA-2777 Buenos Aires, DF, Argentina

[7] Clin Bupa Santiago, Radiol Dept, Av Dept 1455, Santiago, Region Metropol, Chile

来源：

CRITICAL CARE | 2020年 / 24卷 / 01期

关键词：

COVID-19; Coronavirus; Angiotensin converting enzyme 2; Angiotensin II; Vasoconstriction; Vasoplegia; Ventilation-perfusion ratio;

D O I：

10.1186/s13054-020-03125-9

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

[No abstract available]

引用

页数：4

共 12 条

[1] Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology [J].

Channappanavar, Rudragouda ;

Perlman, Stanley .

SEMINARS IN IMMUNOPATHOLOGY, 2017, 39 (05) :529-539

[2] COVID-19 pneumonia: ARDS or not? [J].

Gattinoni, Luciano ;

Chiumello, Davide ;

Rossi, Sandra .

CRITICAL CARE, 2020, 24 (01)

[3] Iodine Maps from Subtraction CT or Dual-Energy CT to Detect Pulmonary Emboli with CT Angiography: A Multiple-Observer Study [J].

Grob, Dagmar ;

Smit, Ewoud ;

Prince, Jip ;

Kist, Jakob ;

Stoger, Lauran ;

Geurts, Bram ;

Snoeren, Miranda M. ;

van Dijk, Rogier ;

Oostveen, Luuk J. ;

Prokop, Mathias ;

Schaefer-Prokop, Cornelia M. ;

Sechopoulos, Ioannis ;

Brink, Monique .

RADIOLOGY, 2019, 292 (01) :197-205

[4] Hypoxaemia related to COVID-19: vascular and perfusion abnormalities on dual-energy CT [J].

Lang, Min ;

Som, Avik ;

Mendoza, Dexter P. ;

Flores, Efren J. ;

Reid, Nicholas ;

Carey, Denston ;

Li, Matthew D. ;

Witkin, Alison ;

Rodriguez-Lopez, Josanna M. ;

Shepard, Jo-Anne O. ;

Little, Brent P. .

LANCET INFECTIOUS DISEASES, 2020, 20 (12) :1365-1366

[5] The Science Underlying COVID-19 Implications for the Cardiovascular System [J].

Liu, Peter P. ;

Blet, Alice ;

Smyth, David ;

Li, Hongliang .

CIRCULATION, 2020, 142 (01) :68-78

[6] Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury [J].

Liu, Yingxia ;

Yang, Yang ;

Zhang, Cong ;

Huang, Fengming ;

Wang, Fuxiang ;

Yuan, Jing ;

Wang, Zhaoqin ;

Li, Jinxiu ;

Li, Jianming ;

Feng, Cheng ;

Zhang, Zheng ;

Wang, Lifei ;

Peng, Ling ;

Chen, Li ;

Qin, Yuhao ;

Zhao, Dandan ;

Tan, Shuguang ;

Yin, Lu ;

Xu, Jun ;

Zhou, Congzhao ;

Jiang, Chengyu ;

Liu, Lei .

SCIENCE CHINA-LIFE SCIENCES, 2020, 63 (03) :364-374

[7] Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases [J].

Magro, Cynthia ;

Mulvey, J. Justin ;

Berlin, David ;

Nuovo, Gerard ;

Salvatore, Steven ;

Harp, Joanna ;

Baxter-Stoltzfus, Amelia ;

Laurence, Jeffrey .

TRANSLATIONAL RESEARCH, 2020, 220 :1-13

[8] Diagnosis, Prevention, and Treatment of Thromboembolic Complications in COVID-19: Report of the National Institute for Public Health of the Netherlands [J].

Oudkerk, Matthijs ;

Buller, Harry R. ;

Kuijpers, Dirkjan ;

van Es, Nick ;

Oudkerk, Sytse F. ;

McLoud, Theresa ;

Gommers, Diederik ;

van Dissel, Jaap ;

ten Cate, Hugo ;

van Beek, Edwin J. R. .

RADIOLOGY, 2020, 297 (01) :E216-E222

[9] The trinity of COVID-19: immunity, inflammation and intervention [J].

Tay, Matthew Zirui ;

Poh, Chek Meng ;

Renia, Laurent ;

MacAry, Paul A. ;

Ng, Lisa F. P. .

NATURE REVIEWS IMMUNOLOGY, 2020, 20 (06) :363-374

[10] Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19 [J].

Vaduganathan, Muthiah ;

Vardeny, Orly ;

Michel, Thomas ;

McMurray, John J., V ;

Pfeffer, Marc A. ;

Solomon, Scott D. .

NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (17) :1653-1659

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