Effect of Ketoconazole on the plasma pharmacokinetics of Axitinib (AG-013736) in healthy volunteers

被引：0
作者：
Pithavala, Yazdi
Klamerus, Karen
Garrett, May
Hee, Brian
Mount, Janessa
Selaru, Paulina
Sarapa, Nenad
机构：
[1] Pfizer Inc, San Diego, CA USA
[2] CPCS Pharma Consulting, Morristown, NJ USA
来源：
CANCER RESEARCH | 2008年 / 68卷 / 09期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
232
引用
收藏
页数：2
相关论文
共 50 条
  • [11] Development of an efficient Pd catalyzed process for Axitinib (AG-013736)
    Srirangam, Jay K.
    Yu, Shu
    Singer, Rob
    Flahive, Erik
    Sach, Neal
    Tian, Qingping
    Babu, Srin
    Saenz, James
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [12] Axitinib (AG-013736) in patients with metastatic melanoma: A phase II study
    Fruehauf, J. P.
    Lutzky, J.
    McDermott, D. F.
    Brown, C. K.
    Pithavala, Y. K.
    Bycott, P. W.
    Shalinsky, D.
    Liau, K. F.
    Niethammer, A.
    Rixe, O.
    JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (15)
  • [13] PHARMACOKINETICS ( PK) OF AXITINIB ( AG-013736; AG) IN SUBJECTS WITH HEPATIC IMPAIRMENT COMPARED WITH THOSE WITH NORMAL HEPATIC FUNCTION.
    Tortorici, M. A.
    Toh, M.
    Rahavendran, S. V.
    LaBadie, R. R.
    Marbury, T.
    Fuentes, E.
    Green, M.
    Ni, G.
    Hee, B.
    Alvey, C. W.
    Pithavala, Y. K.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2010, 87 : S76 - S76
  • [14] A phase 2 study of axitinib (AG-013736; AG) in patients (pts) with advanced thyroid cancers
    Cohen, E.
    Vokes, E. E.
    Rosen, L. S.
    Kies, M. S.
    Forastiere, A. A.
    Worden, F. P.
    Kane, M. A.
    Liau, K. F.
    Shalinsky, D. R.
    Cohen, R. B.
    EJC SUPPLEMENTS, 2007, 5 (04): : 326 - 326
  • [15] A phase II study of axitinib (AG-013736 [AG]) in patients (pts) with advanced thyroid cancers
    Cohen, E. E.
    Vokes, E. E.
    Rosen, L. S.
    Kies, M. S.
    Forastiere, A. A.
    Worden, F. P.
    Kane, M. A.
    Liau, K. F.
    Shalinsky, D. R.
    Cohen, R. B.
    JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (18)
  • [16] A phase II study of axitinib (AG-013736) in patients with incurable adenoid cystic carcinoma
    Ho, A. L.
    Dunn, L.
    Sherman, E. J.
    Fury, M. G.
    Baxi, S. S.
    Chandramohan, R.
    Dogan, S.
    Morris, L. G. T.
    Cullen, G. D.
    Haque, S.
    Sima, C. S.
    Ni, A.
    Antonescu, C. R.
    Katabi, N.
    Pfister, D. G.
    ANNALS OF ONCOLOGY, 2016, 27 (10) : 1902 - 1908
  • [17] Commercial route development for axitinib/AG-013736, solid form and control strategy challenges
    Singer, Robert
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244
  • [18] Effect of axitinib (AG-013736) on thyroid function and biomarkers: Results from phase studies in Japanese patients
    Fujiwara, Yutaka
    Kiyota, Naomi
    Chayahara, Naoko
    Suzuki, Akiyuki
    Umeyama, Yoshiko
    Mukohara, Toru
    Minami, Hironobu
    MOLECULAR CANCER THERAPEUTICS, 2009, 8 (12)
  • [19] Evaluation of the effect of food on the pharmacokinetics of axitinib in healthy volunteers
    Yazdi K. Pithavala
    Ying Chen
    Melvin Toh
    Paulina Selaru
    Robert R. LaBadie
    May Garrett
    Brian Hee
    Janessa Mount
    Grace Ni
    Karen J. Klamerus
    Michael A. Tortorici
    Cancer Chemotherapy and Pharmacology, 2012, 70 : 103 - 112
  • [20] Evaluation of the effect of food on the pharmacokinetics of axitinib in healthy volunteers
    Pithavala, Yazdi K.
    Chen, Ying
    Toh, Melvin
    Selaru, Paulina
    LaBadie, Robert R.
    Garrett, May
    Hee, Brian
    Mount, Janessa
    Ni, Grace
    Klamerus, Karen J.
    Tortorici, Michael A.
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2012, 70 (01) : 103 - 112
12345