COVID-19: progression of disease and intravascular coagulation - present status and future perspectives

被引：51

作者：

Harenberg, Job ^{[1
]}

Favaloro, Emmanuel ^{[2
]}

机构：

[1] Heidelberg Univ, DOASENSE GmbH, Waldhofer Str 102, D-69123 Heidelberg, Germany

[2] Westmead Hosp, Sydney Ctr Thrombosis & Haemostasis, Inst Clin Pathol & Med Res, Dept Haematol,NSW Hlth Pathol, Westmead, NSW, Australia

来源：

CLINICAL CHEMISTRY AND LABORATORY MEDICINE | 2020年 / 58卷 / 07期

关键词：

antibodies; anticoagulation; autopsy; coagulation parameters; COVID-19; D-dimer; disseminated intravascular coagulation; heparin; low-molecular-weight heparin; pulmonary embolism; SARS-CoV-2; thrombosis; SEPSIS;

D O I：

10.1515/cclm-2020-0502

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The timely and accurate diagnosis of infection with severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), remains the cornerstone of efforts to provide appropriated treatment for patients, to limit further spread of the virus and ultimately to eliminate the virus from the human society. We focus this article on (a) developments for improvement of diagnosis of specific SARS-CoV-2 virus, (b) laboratory changes in the immunologic and coagulation system, (c) therapeutic options for anticoagulant treatment of seriously affected patients and (d) on the perspectives through improvement of diagnostic and therapeutic medical procedures.

引用

页码：1029 / 1036

页数：8

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