Ketogenic diet does not change NKCC1 and KCC2 expression in rat hippocampus

被引：11

作者：

Gomez-Lira, Gisela ^{[1
]}

Griselda Mendoza-Torreblanca, Julieta ^{[1
]}

Granados-Rojas, Leticia ^{[1
]}

机构：

[1] Inst Nacl Pediat, Lab Neuromorfometria, Mexico City 04530, DF, Mexico

来源：

EPILEPSY RESEARCH | 2011年 / 96卷 / 1-2期

关键词：

Ketogenic diet; NKCC1; KCC2; Optical fractionator; Hippocampus; Rat; IMMATURE NEOCORTICAL NEURONS; CL-COTRANSPORTER KCC2; KETONE-BODIES; GABA; TRANSPORTERS; EXCITABILITY; ACTIVATION; SEIZURES; MICE;

D O I：

10.1016/j.eplepsyres.2011.05.017

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In control rats, we examined the effects of ketogenic diet on NKCC1 and KCC2 expression levels in hippocampus. Neither the number of NKCC1 immunoreactive cells nor the intensity of labeling of KCC2 was found to modify in hippocampus of the rats after ketogenic diet treatment. These results indicate that ketogenic diet by itself does not modify the expression of these cation chloride cotransporters. (C) 2011 Elsevier B.V. All rights reserved.

引用

页码：166 / 171

页数：6

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