Endothelial progenitor cells and coronary artery disease: Current concepts and future research directions

被引:7
作者
Xiao, Sen-Tong [1 ]
Kuang, Chun-Yan [2 ]
机构
[1] Guizhou Med Univ, Peoples Hosp, Dept Cardiovasc Dis, Guiyang 550003, Guizhou, Peoples R China
[2] Guizhou Prov Peoples Hosp, Dept Cardiovasc Dis, 83 Zhongshan East Rd, Guiyang 550003, Guizhou, Peoples R China
基金
中国国家自然科学基金;
关键词
Endothelial progenitor cells; Coronary disease; Endothelial progenitor-cell capture stents; Endothelial progenitor-cell infusion; Clinical application; CIRCULATION-DERIVED CD34+CELLS; ACUTE MYOCARDIAL-INFARCTION; IN-VITRO DIFFERENTIATION; NECROSIS-FACTOR-ALPHA; INTRACORONARY TRANSFUSION; PROMOTE ANGIOGENESIS; OXIDATIVE STRESS; STENT RESTENOSIS; COMBO STENTS; VESSEL WALL;
D O I
10.12998/wjcc.v9.i30.8953
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Vascular injury is a frequent pathology in coronary artery disease. To repair the vasculature, scientists have found that endothelial progenitor cells (EPCs) have excellent properties associated with angiogenesis. Over time, research on EPCs has made encouraging progress regardless of pathology or clinical technology. This review focuses on the origins and cell markers of EPCs, and the connection between EPCs and coronary artery disease. In addition, we summarized various studies of EPC-capturing stents and EPC infusion therapy, and aim to learn from past technology to predict the future.
引用
收藏
页码:8953 / 8966
页数:14
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