Detecting single porphyrin molecules in a conically shaped synthetic nanopore

被引：236

作者：

Heins, EA

Siwy, ZS

Baker, LA

Martin, CR ^{[1
]}

机构：

[1] Univ Florida, Dept Chem, Gainesville, FL 32611 USA

[2] Univ Florida, Ctr Res Bionano Interface, Gainesville, FL 32611 USA

来源：

NANO LETTERS | 2005年 / 5卷 / 09期

关键词：

D O I：

10.1021/nl050925i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report here the first example of abiotic resistive-pulse sensing of a molecular (as opposed to a particle or macromolecular) analyte. This was accomplished by using a conically shaped nanopore prepared by the track-etch method as the sensing element. It is possible to sense the molecular analyte because the small diameter opening of the conical nanopore (similar to 4.5 nm) is comparable to the diameter of the analyte molecule (similar to 2 nm).

引用

页码：1824 / 1829

页数：6

共 39 条

[1]

[Anonymous], ELECTROCHEMICAL METH

[2] Diode-like single-ion track membrane prepared by electro-stopping [J].