Antimicrobial triterpenoids from Vladimiria muliensis

被引：39

作者：

Chen, Jian-Jun ^{[1
]}

Fei, Dong-Qing ^{[1
]}

Chen, Sheng-Gao ^{[1
]}

Gao, Kun ^{[1
]}

机构：

[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 04期

关键词：

D O I：

10.1021/np070483l

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new triterpenoid with a rearranged ursane skeleton, 3 beta-acetoxyl-11 alpha-methoxybauer-8-en-7 alpha-ol (1), two new ursane triterpenoids, 1 alpha,5 alpha-dioxy- 11 alpha-hydroxyurs-12-en-3-one (2) and urs-3 beta,13 alpha,18 beta-triol (3), together with three known ursane triterpenoids (4-6) were isolated from the rhizome of Vladimiria muliensis. Their structures were elucidated on the basis of spectroscopic methods (IR, EIMS, HRESIMS, ID and 2D NMR, and X-ray crystallography diffraction). Compounds 2 and 4 exhibited modest antimicrobial activity against Escherichia coli, Candida albicans, Pseudomonas aeruginosa, Enterococcus faecalis, Bacillus cereus, and Staphylococcus aureus.

引用

页码：547 / 550

页数：4

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