Design and biosynthesis of functional protein nanostructures

被引:11
作者
Li, Feng [1 ]
Wang, Dianbing [2 ]
Zhou, Juan [1 ]
Men, Dong [1 ]
Zhan, Xian-En [2 ]
机构
[1] Chinese Acad Sci, Wuhan Inst Virol, Ctr Biosafety Mega Sci, State Key Lab Virol, Wuhan 430071, Peoples R China
[2] Chinese Acad Sci, Inst Biophys, CAS Ctr Excellence Biomacromol, Natl Lab Biomacromol, Beijing 100101, Peoples R China
基金
中国国家自然科学基金;
关键词
protein nanostructures; protein nanowires; S-layer; protein nanocages; self-assembly; biosynthesis; functionalization; S-LAYER PROTEINS; VIRUS-LIKE PARTICLES; COWPEA MOSAIC-VIRUS; GOLD NANOPARTICLES; VIRAL NANOPARTICLES; ULTRAFILTRATION MEMBRANES; EXTRACTABLE ANTIGEN; FLUORESCENT PROTEIN; BACILLUS-ANTHRACIS; AMYLOID FIBRILS;
D O I
10.1007/s11427-019-1641-6
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Proteins are one of the major classes of biomolecules that execute biological functions for maintenance of life. Various kinds of nanostructures self-assembled from proteins have been created in nature over millions of years of evolution, including protein nanowires, layers and nanocages. These protein nanostructures can be reconstructed and equipped with desired new functions. Learning from and manipulating the self-assembly of protein nanostructures not only help to deepen our understanding of the nature of life but also offer new routes to fabricate novel nanomaterials for diverse applications. This review summarizes the recent research progress in this field, focusing on the characteristics, functionalization strategies, and applications of protein nanostructures.
引用
收藏
页码:1142 / 1158
页数:17
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