Engineering of a redox protein for DNA-directed assembly

被引:5
|
作者
Szilvay, Geza R. [2 ]
Brocato, Shayna [1 ]
Ivnitski, Dmitri [1 ]
Li, Carol [2 ]
De La Iglesia, Pablo [1 ]
Lau, Carolin [1 ]
Chi, Eva [1 ]
Werner-Washburne, Margaret [3 ]
Banta, Scott [2 ]
Atanassov, Plamen [1 ]
机构
[1] Univ New Mexico, Dept Chem & Nucl Engn, Albuquerque, NM 87131 USA
[2] Columbia Univ, Dept Chem Engn, New York, NY 10027 USA
[3] Univ New Mexico, Dept Biol, Albuquerque, NM 87131 USA
基金
芬兰科学院;
关键词
SMALL LACCASE; HYDROGELS; SLAC;
D O I
10.1039/c1cc11951f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Engineered enzyme conjugate of the small laccase enzyme from Streptomyces coelicolor and zinc finger DNA binding domain from Zif268 is demonstrated to bind double stranded DNA in a site specific manner while retaining enzymatic activity.
引用
收藏
页码:7464 / 7466
页数:3
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