Copper-Catalyzed Bis(methoxycarbonyl)carbene Reactions of α,β-Unsaturated Carboxamides

被引：6

作者：

Merey, Gokce ^{[1
]}

Anac, Olcay ^{[1
]}

机构：

[1] Istanbul Tech Univ, Fac Sci & Letters, Dept Chem, TR-34460 Istanbul, Turkey

来源：

HELVETICA CHIMICA ACTA | 2011年 / 94卷 / 06期

关键词：

DIMETHYL DIAZOMALONATE; DIAZO-COMPOUNDS; ORGANOCATALYTIC CYCLOPROPANATION; STEREOSELECTIVE-SYNTHESIS; ASYMMETRIC-SYNTHESIS; DICARBONYL-COMPOUNDS; YLIDE REACTIONS; DIHYDROFURANS; ALPHA; BETA-ENONES;

D O I：

10.1002/hlca.201000384

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The [Cu(acac)(2)]-catalyzed reactions of alpha,beta-unsaturated carboxamides with dimethyl diazomalonate yielded dihydrofuran derivatives by a 1,5-electrocyclic reaction at C(beta), and butadiene derivatives by carbene addition reaction at C(alpha) (Schemes 4 and 5; Table). Phenyl substituents at the N-atom of the amides seem to be effective on the reaction pathways (Table).

引用

页码：1053 / 1064

页数：12

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