Sorption of anionic polysaccharides and bovine serum albumin on a macroporous glass

Concentration and time dependences of the sorption of alginic acid acid kappa -carrageenan on an MPS- 1000 macroporous glass were studied. The character of pH effect on the sorption of these polysaccharides was established. For a number of sorbents prepared by the preliminary adsorption of polysaccharides on an MPS-1000 glass, the dependence of the sorption of bovine serum albumin (BSA) on the surface content of alginic acid and kappa -carrageenan was studied. The model of adsorption in the silica-polysaccharide-protein system accounting for the interaction between polysaccharide ionic groups and active sites at the sorbent surface and protein molecules was proposed. Acid-base properties of silica modified with polysaccharides were investigated by the potentiometric titration, and the results supporting the validity of the proposed model were obtained.