Successful management of massive lamotrigine extended-release intoxication in a dog

被引：0
作者：
McLaine, Alexis S. [1 ]
Yaxley, Page E. [1 ]
Young, Anda A. [1 ]
Cooper, Edward S. [1 ]
机构：
[1] Ohio State Univ, Dept Vet Clin Sci, Columbus, OH 43210 USA
来源：
CLINICAL CASE REPORTS | 2021年 / 9卷 / 12期
关键词：
cardiovascular disorders; lamotrigine; neurologic disorders; toxicology; veterinary; INTRAVENOUS LIPID EMULSION; PHARMACOLOGICAL-PROPERTIES; PHARMACOKINETICS; TOXICITY; OVERDOSE; CHARCOAL; THERAPY;
D O I：
10.1002/ccr3.5169
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 3-year-old spayed female Siberian Husky presented for evaluation following ingestion of approximately 429 mg/kg of lamotrigine extended-release. She demonstrated severe neurologic and cardiac signs and was treated with lipid emulsion, anticonvulsants, antiarrhythmics and aggressive decontamination and supportive care. She was successfully discharged from the hospital 5 days later.
引用
收藏
页数：10
相关论文
共 50 条
  • [21] USL255 extended-release topiramate for the treatment of epilepsy
    Chung, Steve
    EXPERT REVIEW OF NEUROTHERAPEUTICS, 2014, 14 (10) : 1127 - 1137
  • [22] A comparison of the pharmacokinetics of two different formulations of extended-release niacin
    Lauring, B.
    Rosko, K.
    Luo, W. -L.
    Wenning, L.
    Kissling, J.
    Roupe, K.
    Paolini, J. F.
    Wagner, J.
    Lai, E.
    CURRENT MEDICAL RESEARCH AND OPINION, 2009, 25 (01) : 15 - 22
  • [23] Successful management of minoxidil toxicosis in a dog
    Jordan, Tyler J. M.
    Yaxley, Page E.
    Culler, Christine A.
    Balakrishnan, Anusha
    JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 2018, 252 (02): : 222 - 226
  • [24] The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet
    Menon, R.
    Tolbert, D.
    Cefali, E.
    BIOPHARMACEUTICS & DRUG DISPOSITION, 2007, 28 (06) : 297 - 306
  • [25] Use of haemodiafiltration in the treatment of massive caffeine intoxication in a dog
    Gordon, Daniel S.
    Langston, Cathy E.
    VETERINARY MEDICINE AND SCIENCE, 2023, 9 (04) : 1460 - 1464
  • [26] Release mechanisms and applications of drug delivery systems for extended-release
    Wang, Shuying
    Liu, Renhe
    Fu, Yao
    Kao, W. John
    EXPERT OPINION ON DRUG DELIVERY, 2020, 17 (09) : 1289 - 1304
  • [27] Extended-release drug formulations for the treatment of epilepsy
    Brandt, Christian
    May, Theodor W.
    EXPERT OPINION ON PHARMACOTHERAPY, 2018, 19 (08) : 843 - 850
  • [28] Extended-Release Mesalamine Granules for Ulcerative Colitis
    Love, Bryan L.
    Miller, April D.
    ANNALS OF PHARMACOTHERAPY, 2012, 46 (11) : 1529 - 1536
  • [29] Design and evaluation of nicorandil extended-release tablet
    Kim, Ju-Young
    Park, Chun-Woong
    Lee, Beom-Jin
    Park, Eun-Seok
    Rhee, Yun-Seok
    ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, 10 (02) : 108 - 113
  • [30] Review of extended-release formulations of Tramadol for the management of chronic non-cancer pain: focus on marketed formulations
    Kizilbash, Arshi
    Cu'ong Ngo-Minh
    JOURNAL OF PAIN RESEARCH, 2014, 7 : 149 - 161
12345