Scientific and Technological Prospecting of 1H-1,2,3-Triazoles

被引：0

作者：

Alves Caiana, Rodrigo Ribeiro ^{[1
]}

Santos, Cosme Silva ^{[2
]}

de Oliveira, Ronaldo Nascimento ^{[2
]}

Rufino Freitas, Juliano Carlo ^{[1
,2
]}

机构：

[1] Univ Fed Campina Grande, Ctr Educ & Hlth, BR-58175000 Cuite, PB, Brazil

[2] Univ Fed Rural Pernambuco, Dept Chem, BR-52171900 Recife, PE, Brazil

来源：

CURRENT ORGANIC CHEMISTRY | 2022年 / 26卷 / 03期

关键词：

Heterocycles; 1,2,3-triazole; cycloaddition; click chemistry; intellectual property; patents; innovation; AZIDE-ALKYNE CYCLOADDITION; CB1 RECEPTOR ANTAGONISTS; CATALYZED CYCLOADDITION; CLICK CHEMISTRY; BIOLOGICAL-ACTIVITY; TERMINAL ALKYNES; 1,2,3-TRIAZOLES; DERIVATIVES; INHIBITORS; PHASE;

D O I：

10.2174/1385272826666220126153429

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of 1H-1,2,3-triazoles has become an important scaffold for applications in different technological sectors. Therefore, we sought to carry out technological monitoring to understand the international scenario involving 1H-1,2,3-triazoles from the patents filed, in addition to evaluating the relationship between the growth in the number of patents and the improvement of strategies for obtaining these compounds via a metal-catalyzed azide-alkyne cycloaddition reaction. Technological monitoring was performed with the support of the PatentInspiration (R) platform, using the keywords "1.2.3-triazol", "1,2,3-triazole", and "1.2,3-triazolyl". A total of 960 registered patents were found, most for the years 2014 and 2019. The main filers were prestigious multinational companies, such as Syngenta, Merck, Sandoz, Pfizer, and Bayer. The United States, China, Japan. and Germany lead patent registrations, mainly addressing innovations in chemistry and metallurgy, human needs, and new technologies. These results help to understand the state of innovation for this topic, pointing out the characteristics of the main discoveries concerning 1H-1,2,3-triazole derivatives.

引用

页码：275 / 286

页数：12

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