Efficient bromination of olefins, alkynes, and ketones with dimethyl sulfoxide and hydrobromic acid

被引：102

作者：

Song, Song ^{[1
]}

Li, Xinwei ^{[1
]}

Sun, Xiang ^{[1
]}

Yuan, Yizhi ^{[1
]}

Jiao, Ning ^{[1
,2
]}

机构：

[1] Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

[2] E China Normal Univ, Dept Chem, Shanghai Key Lab Green Chem & Chem Proc, Shanghai 200062, Peoples R China

来源：

GREEN CHEMISTRY | 2015年 / 17卷 / 06期

基金：

中国国家自然科学基金;

关键词：

OXIDATIVE BROMINATION; METHYL KETONES; CHEMICAL OXIDATION; MOLECULAR-OXYGEN; AMMONIUM BROMIDE; FACILE SYNTHESIS; ALKENES; DMSO; DIBROMINATION; HALOGENATION;

D O I：

10.1039/c5gc00528k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The oxidative bromination of olefins, alkynes, and ketones has been developed with HBr as the brominating reagent and DMSO as the mild oxidant. The simple conditions, high bromide-atom-economy, as well as easy accessibility and low cost of DMSO and HBr make the present strategy prospective for the synthesis of dibrominated alkanes, dibrominated alkenes and alpha-bromoketones.

引用

页码：3285 / 3289

页数：5

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