A short dipolar cycloaddition approach to gamma-lactam alkaloids from Cynometra hankei

被引：44

作者：

Fishwick, CWG ^{[1
]}

Foster, RJ ^{[1
]}

Carr, RE ^{[1
]}

机构：

[1] GLAXO WELLCOME RES & DEV LTD,MED RES CTR,STEVENAGE SG1 2NY,HERTS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 22期

关键词：

D O I：

10.1016/0040-4039(96)00688-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The gamma-lactam based alkaloid cynometrine has been synthesised in four steps from 1-methyl-imidazole-4-carboxaldehyde. The key step involves an efficient regio-, stereo-, and chemoselective 1,3-dipolar cycloaddition of a dithiolane-fused azomethine ylide. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：3915 / 3918

页数：4

共 11 条

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