Evaluation of oxidant, antioxidant, and S100B levels in patients with conversion disorder

被引：4

作者：

Buyukaslan, Hasan ^{[1
]}

Kandemir, Sultan Basmaci ^{[2
]}

Asoglu, Mehmet ^{[3
]}

Kaya, Halil ^{[4
]}

Gokdemir, Mehmet Tahir ^{[1
]}

Karababa, Ibrahim Fatih ^{[3
]}

Gungormez, Fatih ^{[5
]}

Kilicaslan, Fethiye ^{[6
]}

Savik, Emin ^{[7
]}

机构：

[1] Harran Univ, Dept Emergency Med, Fac Med, Meteorol St, TR-63300 Sanliurfa, Turkey

[2] Harran Univ, Balikligol State Hosp, Dept Psychiat, Sanliurfa, Turkey

[3] Harran Univ, Fac Med, Dept Psychiat, Sanliurfa, Turkey

[4] Bursa Yuksek Ihtisas Training & Res Hosp, Bursa, Turkey

[5] Harran Univ, Dept Emergency Med, Mehmet Akif Inan Res Hosp, Sanliurfa, Turkey

[6] Harran Univ, Dept Child & Adolescent Psychiat, Fac Med, Sanliurfa, Turkey

[7] Harran Univ, Dept Biochem, Fac Med, Sanliurfa, Turkey

来源：

NEUROPSYCHIATRIC DISEASE AND TREATMENT | 2016年 / 12卷

关键词：

conversion disorder; oxidative stress; S100B; DEFICIT HYPERACTIVITY DISORDER; OBSESSIVE-COMPULSIVE DISORDER; SCHIZOPHRENIC-PATIENTS; OXIDATIVE STRESS; DEPRESSIVE EPISODES; ADOLESCENT PATIENTS; BIPOLAR DISORDER; MAJOR DEPRESSION; SERUM-LEVELS; PROTEIN;

D O I：

10.2147/NDT.S109174

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction: Various psychodynamic, neurobiological, genetic, and sociocultural factors are believed to be involved in the etiology of conversion disorder (CD). Oxidative metabolism has been shown to deteriorate in association with many health problems and psychiatric disorders. We evaluated oxidative metabolism and S100B levels in the context of this multifactorial disease. Methods: Thirty-seven patients with CD (25 females and 12 males) and 42 healthy volunteers (21 females and 21 males), all matched for age and sex, were included in this study. The total oxidant status, total antioxidant status, oxidative stress index, and S100B levels were compared between the two groups. Results: The total oxidant status, oxidative stress index, and S100B levels were significantly higher in patients with CD than in the control group, whereas the total antioxidant status was significantly lower. Conclusion: CD is associated with deterioration of oxidative metabolism and increased neuronal damage.

引用

页码：1725 / 1729

页数：5

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