Effects of slow repetitive transcranial magnetic stimulation in patients with corticobasal syndrome

被引：5
|
作者：
Civardi, Carlo [1 ]
Pisano, Fabrizio [2 ]
Delconte, Carmen [2 ]
Collini, Alessandra [3 ]
Monaco, Francesco [1 ]
机构：
[1] Univ Maggiore Carita, Azienda Osped, Clin Neurol, I-28100 Novara, Italy
[2] Fdn Maugeri IRCCS, Neurol Riabilitativa, Veruno, Italy
[3] ASL TO4, Dept Neurol, Chivasso, Italy
来源：
NEUROLOGICAL SCIENCES | 2015年 / 36卷 / 06期
关键词：
Corticobasal syndrome; Transcranial magnetic stimulation; Cortical excitability; Treatment; Slow repetitive transcranial magnetic stimulation; TMS;
D O I：
10.1007/s10072-015-2115-3
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Corticobasal syndrome is characterized by asymmetric cortical sensorimotor dysfunction and parkinsonism; an altered cortical excitability has been reported. We explored with transcranial magnetic stimulation the motor cortical excitability in corticobasal syndrome, and the effects of slow repetitive transcranial magnetic stimulation. With transcranial magnetic stimulation, we studied two corticobasal syndrome patients. We determined bilaterally from the first dorsal interosseous muscle: relaxed threshold, and contralateral and ipsilateral silent period. We also evaluated the contralateral silent period after active/sham slow repetitive transcranial magnetic stimulation on the most affected side. At T0 the silent period was bilaterally short. On the most affected side, active slow repetitive transcranial magnetic stimulation induced a short lasting prolongation of the contralateral silent period. In corticobasal syndrome, transcranial magnetic stimulation showed a reduction cortical inhibitory phenomenon potentially reversed transiently by slow repetitive transcranial magnetic stimulation.
引用
收藏
页码：1007 / 1009
页数：3
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