Graphene Oxide/Multiwalled Carbon Nanotubes Assisted Serial Quadruple Tapered Structure-Based LSPR Sensor for Glucose Detection

被引：100

作者：

Li, Guoru ^{[1
]}

Xu, Qing ^{[2
]}

Singh, Ragini ^{[3
]}

Zhang, Wen ^{[1
]}

Marques, Carlos ^{[4
]}

Xie, Yiyan ^{[1
]}

Zhang, Bingyuan ^{[1
]}

Kumar, Santosh ^{[1
]}

机构：

[1] Liaocheng Univ, Sch Phys Sci & Informat Technol, Shandong Key Lab Opt Commun Sci & Technol, Liaocheng 252059, Shandong, Peoples R China

[2] Shandong Univ, Inst Novel Semicond, State Key Lab Crystal Mat, Jinan 250100, Peoples R China

[3] Liaocheng Univ, Coll Agron, Liaocheng 252059, Shandong, Peoples R China

[4] Univ Aveiro, Dept Phys, I3N, P-3810193 Aveiro, Portugal

来源：

IEEE SENSORS JOURNAL | 2022年 / 22卷 / 17期

基金：

中国国家自然科学基金;

关键词：

Sensors; Probes; Optical fiber sensors; Glucose; Biochemistry; Claddings; Sensitivity; Optical fiber biosensor; nanoparticles; glucose; serial quadruple taper; localized surface plasmon resonance; LABEL-FREE; FIBER; BIOSENSOR;

D O I：

10.1109/JSEN.2022.3193455

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Glucose, an essential nutrient to the metabolism of organisms, is closely related to human health. Here, a novel serial quadruple tapered structure-based localized surface plasmon resonance (LSPR) sensor is employed to achieve accurate detection of glucose level in the human body. Gold nanoparticles (AuNPs) are immobilized on the serial quadruple taper fiber (SQTF) to induce LSPR. Furthermore, graphene oxide (GO) and multi-wall carbon nanotubes (MWCNTs) are used to increase the binding sites of enzymes to improve the sensing performance of probe. In our work, the SQTF probe surface is functionalized with glucose oxidase (GOx) enzyme to enhance selectivity. The sensitivity and limit of detection (LOD) of functionalized probe structure are 1.04 nm/mM and 0.24 mM over a linear range of 0 mM to10 mM, respectively. In addition, the reusability, reproducibility, stability and selectivity of SQTF probe are assessed to demonstrate the potential in measuring glucose content in the human body.

引用

页码：16904 / 16911

页数：8

共 40 条

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