Concurrent carbogen and radiation therapy in children with high-risk brainstem gliomas

被引：18

作者：

Aquino-Parsons, C. ^{[1
]}

Hukin, J. ^{[2
]}

Green, A. ^{[1
]}

机构：

[1] BC Canc Agcy, Vancouver Canc Ctr, Dept Radiat Oncol, Vancouver, BC, Canada

[2] BC Womens & Childrens Hosp, Dept Pediat Oncol, Vancouver, BC, Canada

来源：

PEDIATRIC BLOOD & CANCER | 2008年 / 50卷 / 02期

关键词：

carbogen; brainstem glioma; hypoxia; radiotherapy;

D O I：

10.1002/pbc.21057

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In an attempt to improve local control, we assessed the feasibility of the addition of 4 min of carbogen inhalation (as a radiosensitizer) to daily fractionated radiotherapy in pediatric patients with high grade and/or diffuse brainstem gliomas. Ten patients inhaled carbogen for > 90% of the radiation treatments. Median survival time from start of therapy was 0.80 years. Carbogen inhalation did not appear to improve the dismal prognosis.

引用

页码：397 / 399

页数：3

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