Five new diarylheptanoids from the rhizomes of Curcuma kwangsiensis and their antiproliferative activity

被引：22
作者：
Chen, Shao-Dan [1 ,2 ,3 ]
Gao, Jin-Tao [1 ,2 ]
Liu, Jing-Gong [1 ,2 ]
Liu, Bo [1 ,2 ]
Zhao, Rui-Zhi [1 ,2 ]
Lu, Chuan-Jian [1 ,2 ]
机构：
[1] Guangzhou Univ Chinese Med, Clin Coll 2, Guangzhou 510000, Guangdong, Peoples R China
[2] Guangdong Prov Hosp Chinese Med, Guangzhou 510000, Guangdong, Peoples R China
[3] Guangzhou Univ Chinese Med, Postdoctoral Programme, Guangzhou 510000, Guangdong, Peoples R China
来源：
FITOTERAPIA | 2015年 / 102卷
关键词：
Curcuma kwangsiensis; Diarylheptanoids; Antiproliferation; HH cells; HaCaT cells; CYCLIC DIARYLHEPTANOIDS; ZINGIBER-OFFICINALE; CONSTITUENTS; SESQUITERPENOIDS; DRUGS;
D O I：
10.1016/j.fitote.2015.02.004
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Five new diarylheptanoids (1-5), along with nine known ones (6-14), were isolated from the rhizomes of Curcuma kwangsiensis. Their structures were established on the basis of spectroscopic analyses. Compounds 1-3 were cyclic diarylheptanoids rarely discovered from C. kwangsiensis. Of all the isolated compounds, compound 4 showed moderate antiproliferative activity on HH and HaCaT cells. (C) 2015 Published by Elsevier B.V.
引用
收藏
页码：67 / 73
页数：7
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