Five new diarylheptanoids from the rhizomes of Curcuma kwangsiensis and their antiproliferative activity

被引：22

作者：

Chen, Shao-Dan ^{[1
,2
,3
]}

Gao, Jin-Tao ^{[1
,2
]}

Liu, Jing-Gong ^{[1
,2
]}

Liu, Bo ^{[1
,2
]}

Zhao, Rui-Zhi ^{[1
,2
]}

Lu, Chuan-Jian ^{[1
,2
]}

机构：

[1] Guangzhou Univ Chinese Med, Clin Coll 2, Guangzhou 510000, Guangdong, Peoples R China

[2] Guangdong Prov Hosp Chinese Med, Guangzhou 510000, Guangdong, Peoples R China

[3] Guangzhou Univ Chinese Med, Postdoctoral Programme, Guangzhou 510000, Guangdong, Peoples R China

来源：

FITOTERAPIA | 2015年 / 102卷

关键词：

Curcuma kwangsiensis; Diarylheptanoids; Antiproliferation; HH cells; HaCaT cells; CYCLIC DIARYLHEPTANOIDS; ZINGIBER-OFFICINALE; CONSTITUENTS; SESQUITERPENOIDS; DRUGS;

D O I：

10.1016/j.fitote.2015.02.004

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Five new diarylheptanoids (1-5), along with nine known ones (6-14), were isolated from the rhizomes of Curcuma kwangsiensis. Their structures were established on the basis of spectroscopic analyses. Compounds 1-3 were cyclic diarylheptanoids rarely discovered from C. kwangsiensis. Of all the isolated compounds, compound 4 showed moderate antiproliferative activity on HH and HaCaT cells. (C) 2015 Published by Elsevier B.V.

引用

页码：67 / 73

页数：7

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