Evaluation of the economic burden of Herpes Zoster (HZ) infection A systematic literature review

被引:32
作者
Panatto, Donatella [1 ]
Bragazzi, Nicola Luigi [1 ]
Rizzitelli, Emanuela [1 ]
Bonanni, Paolo [2 ]
Boccalini, Sara [2 ]
Icardi, Giancarlo [1 ]
Gasparini, Roberto [1 ]
Amicizia, Daniela [1 ]
机构
[1] Univ Genoa, Dept Hlth Sci, Genoa, Italy
[2] Univ Florence, Dept Hlth Sci, I-50121 Florence, Italy
关键词
Herpes zoster; Post-herpetic neuralgia; systematic review; economic burden; direct and indirect cost; HEALTH-CARE COSTS; POSTHERPETIC NEURALGIA; RESOURCE UTILIZATION; VARICELLA VACCINE; MEDICAID PATIENTS; EPIDEMIOLOGY; IMMUNITY; IMPACT; US; HOSPITALIZATIONS;
D O I
10.4161/hv.36160
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The main objective of this systematic review was to evaluate the economic burden of Herpes Zoster (HZ) infection. The review was conducted in accordance with the standards of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The following databases were accessed: ISI/Web of Knowledge (WoS), MEDLINE/PubMed, Scopus, ProQuest, the Cochrane Library and EconLit. Specific literature on health economics was also manually inspected. Thirty-three studies were included. The quality of the studies assessed in accordance with the Consolidated Health Economic Evaluation Reporting Standards checklist was good. All studies evaluated direct costs, apart from one which dealt only with indirect costs. Indirect costs were evaluated by 12 studies. The economic burden of HZ has increased over time. HZ management and drug prescriptions generate the highest direct costs. While increasing age, co-morbidities and drug treatment were found to predict higher direct costs, being employed was correlated with higher indirect costs, and thus with the onset age of the disease. Despite some differences among the selected studies, particularly with regard to indirect costs, all concur that HZ is a widespread disease which has a heavy social and economic burden.
引用
收藏
页码:245 / 262
页数:18
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