Recurrent rhabdoid meningioma with lymph node, pulmonary and bone metastases: a diagnostic and therapeutic challenge

被引:5
|
作者
Kakkar, Aanchal [1 ]
Baghmar, Saphalta [2 ]
Garg, Ajay [3 ]
Suri, Vaishali [1 ]
Raina, Vinod [2 ]
Sarkar, Chitra [1 ]
Sharma, Mehar Chand [1 ]
机构
[1] All India Inst Med Sci, Dept Pathol, New Delhi 110029, India
[2] All India Inst Med Sci, Dept Med Oncol, New Delhi 110029, India
[3] All India Inst Med Sci, Dept Neuroradiol, New Delhi 110029, India
关键词
Rhabdoid; Meningioma; Metastases; Lymph node; Immunohistochemistry; TRANSFORMATION; EXPRESSION; PATIENT; TUMOR;
D O I
10.1007/s10014-016-0250-z
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Rhabdoid meningioma is a rare meningioma variant, classified as WHO grade III. Although this tumor is known for its aggressive behavior and poor prognosis, extracranial metastasis is rare. We report the rare case of a 31-year-old patient with rhabdoid meningioma which recurred several times despite gross total resection, radiation therapy, and gamma knife radiosurgery, and the last recurrence was associated with metastases to lungs, lymph node and bone. The patient showed no response to paclitaxel-carboplatin, or vincristine-cyclophosphamide-adriamycin chemotherapy, and succumbed to the disease. Metastases from rhabdoid meningioma prove to be a diagnostic challenge, and treatment for metastatic meningiomas is not optimized, thus necessitating documentation and interdisciplinary consensus on management protocols.
引用
收藏
页码:228 / 233
页数:6
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