A systematic review identifying outcomes and outcome measures in Dupuytren's disease research

被引：19

作者：

Karpinski, Marta ^{[1
]}

Moltaji, Syena ^{[2
]}

Baxter, Charmaine ^{[3
]}

Murphy, Jessica ^{[3
]}

Petropoulos, Jo-Anne ^{[4
]}

Thoma, Achilleas ^{[3
,5
,6
]}

机构：

[1] McMaster Univ, Fac Hlth Sci, Hamilton, ON, Canada

[2] McMaster Univ, Michael G DeGroote Sch Med, Hamilton, ON, Canada

[3] McMaster Univ, Div Plast Surg, Hamilton, ON, Canada

[4] McMaster Univ, Hlth Sci Lib, Hamilton, ON, Canada

[5] McMaster Univ, Dept Surg, Hamilton, ON, Canada

[6] McMaster Univ, Dept Hlth Res Methods Evidence & Impact, Hamilton, ON, Canada

来源：

JOURNAL OF HAND SURGERY-EUROPEAN VOLUME | 2020年 / 45卷 / 05期

关键词：

Dupuytren; outcome; outcome definition; measure; reporting; core outcome set; COLLAGENASE CLOSTRIDIUM-HISTOLYTICUM; PERCUTANEOUS NEEDLE FASCIOTOMY; INJECTABLE COLLAGENASE; LIMITED FASCIECTOMY; SURGICAL-TREATMENT; JAPANESE PATIENTS; CLINICAL-TRIAL; HAND THERAPY; CONTRACTURE; SAFETY;

D O I：

10.1177/1753193420903624

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

This systematic review summarizes the outcome reporting standards in Dupuytren's disease treatment research. A search of Ovid Medline, Ovid Embase, and CINAHL was conducted. Randomized controlled trials, cohort studies, and case series published between 1997 and 2017, investigating treatment of Dupuytren's disease with fasciectomy, fasciotomy, or collagenase, were eligible for inclusion. Range of motion was the most commonly reported outcome, appearing in 77% of included studies. Outcomes, such as range of motion, recurrence, and clinical success, were frequently defined, however many different definitions were used. We identified 37 unique measurement methods for range of motion, 28 for recurrence, and 25 for clinical success. Most outcomes were assessed at multiple time points, and only a few studies reported results according to established clinical significance thresholds. Development of a core outcome set will help standardize outcome reporting, and ensure future research in this field is relevant, interpretable, and amenable to systematic review and/or meta-analysis.

引用

页码：513 / 520

页数：8

共 70 条

[31] Efficacy and safety of collagenase Clostridium histolyticum injection for Dupuytren's contracture in non-Caucasian Japanese patients (CORD-J Study): the first clinical trial in a non-Caucasian population [J].