The role of presepsin in the diagnosis of chronic obstructive pulmonary disease acute exacerbation with pneumonia

被引：13
作者：
Halici, Ali [1 ]
Hur, Zzettin [1 ]
Abatay, Kerim [1 ]
Cetin, Esra [2 ]
Halici, Filiz [3 ]
Ozkan, Seda [4 ]
机构：
[1] Univ Hlth Sci, Diskapi Yildirim Beyazit Training & Res Hosp, Dept Emergency Med, TR-06145 Ankara, Turkey
[2] Univ Hlth Sci, Diskapi Yildirim Beyazit Training & Res Hosp, Dept Biochem, TR-06145 Ankara, Turkey
[3] Univ Hlth Sci, Diskapi Yildirim Beyazit Training & Res Hosp, Dept Family Med, TR-06145 Ankara, Turkey
[4] Univ Istanbul Cerrahpasa, Fac Med, Dept Emergency Med, TR-34098 Istanbul, Turkey
来源：
BIOMARKERS IN MEDICINE | 2020年 / 14卷 / 01期
关键词：
acute exacerbation; C-reactive protein; COPD; diagnosis; erythrocyte sedimentation rate; pneumonia; presepsin; procalcitonin; SOLUBLE CD14 SUBTYPE; C-REACTIVE PROTEIN; COMMUNITY-ACQUIRED PNEUMONIA; INFLAMMATORY RESPONSE; COPD EXACERBATIONS; SCD14-ST; SEPSIS;
D O I：
10.2217/bmm-2019-0183
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Aim: In this study, we aimed to investigate the role of presepsin in detecting concomitant pneumonia in patients presenting with acute exacerbation of chronic obstructive pulmonary disease (COPD) in the emergency department. Patients & methods: Three groups were formed in the study. Group 1: patients diagnosed with acute exacerbation of COPD; group 2: patients with acute exacerbation of COPD + pneumonia; group 3: healthy individuals. Results: Presepsin levels of the patients in group 2 were significantly higher than those of group 1 and group 3 (p < 0.05). There was a statistically significant difference in erythrocyte sedimentation rate, CRP, procalcitonin and presepsin values between two patient groups (p < 0.05). Conclusion: Presepsin can be used to diagnose pneumonia in patients with acute exacerbation of COPD admitted to the emergency department.
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收藏
页码：31 / 41
页数：11
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