Intermolecular Markovnikov-Selective Hydroacylation of Olefins Catalyzed by a Cationic Ruthenium-Hydride Complex

被引：26

作者：

Kim, Junghwa ^{[1
]}

Yi, Chae S. ^{[1
]}

机构：

[1] Marquette Univ, Dept Chem, Milwaukee, WI 53201 USA

来源：

ACS CATALYSIS | 2016年 / 6卷 / 05期

基金：

美国国家科学基金会;

关键词：

hydroacylation; alkene; aldehyde; ruthenium catalyst; branched ketone; ALDEHYDE OXIDATION LEVEL; C-H ALKYLATION; INTRAMOLECULAR HYDROACYLATION; BETA; GAMMA-UNSATURATED KETONES; ASYMMETRIC CATALYSIS; BOND ACTIVATION; ALCOHOLS; ALKENES; FUNCTIONALIZATION; MECHANISM;

D O I：

10.1021/acscatal.6b00856

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The cationic Ru-H complex was found to be an effective catalyst for the intermolecular hydroacylation of aryl-substituted olefins with aldehydes to form branched ketone products. The preliminary kinetic and spectroscopic studies elucidated a ruthenium-acyl complex as the key intermediate species. The catalytic method directly afforded branched ketone products in a highly regioselective manner while tolerating a number of heteroatom functional groups.

引用

收藏

页码：3336 / 3339

页数：4

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