Impact of physical frailty on the clinical outcomes of older patients hospitalized for pneumonia

被引:5
作者
Yamada, Kanji [1 ,2 ]
Iwata, Kentaro [1 ,2 ]
Tachikawa, Ryo [3 ]
Yoshimura, Yoshihiro [4 ]
Kanejima, Yuji [1 ,2 ]
Yamamoto, Akio [5 ]
Ono, Kumiko [2 ]
Honda, Akihiro [1 ]
Kohara, Nobuo [1 ]
Tomii, Keisuke [3 ]
Ishikawa, Akira [2 ]
Kitai, Takeshi [1 ,5 ]
机构
[1] Kobe City Med Ctr Gen Hosp, Dept Rehabil, Kobe, Hyogo, Japan
[2] Kobe Univ, Dept Publ Hlth, Grad Sch Hlth Sci, Kobe, Hyogo, Japan
[3] Kobe City Med Ctr Gen Hosp, Dept Resp Med, Kobe, Hyogo, Japan
[4] Kumamoto Rehabil Hosp, Ctr Sarcopenia & Malnutr Res, Kumamoto, Japan
[5] Natl Cerebral & Cardiovasc Ctr, Dept Cardiovasc Med, Kishibe Shinmachi, Osaka 5648565, Japan
关键词
activities of daily living; elderly frail; mortality; patient readmission; pneumonia; MORTALITY; ASSOCIATION; PERFORMANCE; DISABILITY; PREDICTOR; ADULTS;
D O I
10.1111/ggi.14262
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Aim This study aimed to assess the association between physical frailty and clinical outcomes among older patients hospitalized for pneumonia. Methods This study examined 852 consecutive patients hospitalized for pneumonia between October 2018 and September 2020. Patients who were <65 years old, scheduled for admission, did not receive inpatient rehabilitation, or died during admission were excluded. A short physical performance battery (SPPB) test was performed by physical therapists upon discharge. The primary outcome measure was a composite endpoint of readmission or mortality due to any cause within 6 months of discharge. Results In total, 521 patients (median age, 80 years; interquartile range, 74-86 years) were included in the analyses, and were divided into the following two groups: robust group with SPPB scores >9 (n = 150), and physical frailty group with SPPB scores <= 9 (n = 371). Of these, 346 (66.4%) patients were men; and the median SPPB score was 6 (interquartile range, 1-10). During the median follow-up period of 53 days (interquartile range, 4-180 days), 92 (17.6%) patients were readmitted and 25 (4.8%) patients died. Patients with physical frailty were at an increased risk for the primary endpoint (hazard ratio, 2.21; 95% confidence interval, 1.44-3.41; P < 0.001); the risk remained significant after adjusting for multiple variables (adjusted hazard ratio, 1.70; 95% confidence interval, 1.05-2.74; P = 0.028). Conclusions Among older patients with pneumonia, physical frailty status at discharge was an independent risk factor for readmission and mortality within 6 months after initial discharge. Geriatr Gerontol Int center dot center dot; center dot center dot: center dot center dot-center dot center dot Geriatr Gerontol Int 2021; center dot center dot: center dot center dot-center dot center dot.
引用
收藏
页码:926 / 931
页数:6
相关论文
共 50 条
[31]   Obesity and outcomes in patients hospitalized with pneumonia [J].
Kahlon, S. ;
Eurich, D. T. ;
Padwal, R. S. ;
Malhotra, A. ;
Minhas-Sandhu, J. K. ;
Marrie, T. J. ;
Majumdar, S. R. .
CLINICAL MICROBIOLOGY AND INFECTION, 2013, 19 (08) :709-716
[32]   The association of frailty with clinical and economic outcomes among hospitalized older adults with hip fracture surgery [J].
M.J. Kwak ;
B.D. Digbeu ;
J. des Bordes ;
N. Rianon .
Osteoporosis International, 2022, 33 :1477-1484
[33]   The association of frailty with clinical and economic outcomes among hospitalized older adults with hip fracture surgery [J].
Kwak, M. J. ;
Digbeu, B. D. ;
des Bordes, J. ;
Rianon, N. .
OSTEOPOROSIS INTERNATIONAL, 2022, 33 (07) :1477-1484
[34]   Age Group Analysis of Psychological, Physical and Functional Deterioration in Patients Hospitalized for Pneumonia [J].
Martin-Salvador, Adelina ;
Torres-Sanchez, Irene ;
Saez-Roca, German ;
Lopez-Torres, Isabel ;
Rodriguez-Alzueta, Elisabeth ;
Carmen Valenza, Marie .
ARCHIVOS DE BRONCONEUMOLOGIA, 2015, 51 (10) :496-501
[35]   Clinical characteristics and outcomes of hospitalized COVID-19 pneumonia : impact of gender [J].
Debiche, Soumaya ;
Sahnoun, Imen ;
Ben Mansour, Ameni ;
Zaafouri, Asma ;
Ben Sassi, Sarra ;
Ben Saad, Soumaya ;
Dabbebi, Fatma Ezzahra ;
Daghfous, Hafaoua ;
Maalej, Sonia ;
Tritar, Fatma ;
El Gharbi, Leila Douik .
EUROPEAN RESPIRATORY JOURNAL, 2021, 58
[36]   Short physical performance battery discriminates clinical outcomes in hospitalized patients aged 75 years and over [J].
Fujita, Kosuke ;
Nakashima, Hirotaka ;
Kako, Masato ;
Shibata, Atsushi ;
Cheng Yu-ting ;
Tanaka, Shinya ;
Nishida, Yoshihiro ;
Kuzuya, Masafumi .
ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2020, 90
[37]   Comparing clinical outcomes in HIV-infected and uninfected older men hospitalized with community-acquired pneumonia [J].
Barakat, L. A. ;
Juthani-Mehta, M. ;
Allore, H. ;
Trentalange, M. ;
Tate, J. ;
Rimland, D. ;
Pisani, M. ;
Akguen, K. M. ;
Goetz, M. B. ;
Butt, A. A. ;
Rodriguez-Barradas, M. ;
Duggal, M. ;
Crothers, K. ;
Justice, A. C. ;
Quagliarello, V. J. .
HIV MEDICINE, 2015, 16 (07) :421-430
[38]   Combined Impact of Positive Screen for Sarcopenia and Frailty on Physical Function, Cognition and Nutrition in the Community Dwelling Older Adult [J].
Lee, Hsien Xiong ;
Yeo, Audrey ;
Tan, Cai Ning ;
Yew, Suzanne ;
Tay, Laura ;
Ding, Yew Yoong ;
Lim, Wee Shiong .
ANNALS OF GERIATRIC MEDICINE AND RESEARCH, 2021, 25 (03) :210-216
[39]   Frailty and Risk of Adverse Outcomes in Hospitalized Older Adults: A Comparison of Different Frailty Measures [J].
Chong, Edward ;
Ho, Esther ;
Baldevarona-Llego, Jewel ;
Chan, Mark ;
Wu, Lynn ;
Tay, Laura .
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2017, 18 (07) :638.e7-638.e11
[40]   Degree of Peripheral Thyroxin Deiodination, Frailty, and Long-Term Survival in Hospitalized Older Patients [J].
Pasqualetti, Giuseppe ;
Calsolaro, Valeria ;
Bernardini, Sara ;
Linsalata, Giuseppe ;
Bigazzi, Renato ;
Caraccio, Nadia ;
Monzani, Fabio .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2018, 103 (05) :1867-1876