Controlled navigation of endoscopic capsules: Concept and preliminary experimental investigations

被引:75
作者
Carpi, Federico
Galbiati, Stefano
Carpi, Angelo
机构
[1] Univ Pisa, Sch Engn, Interdepartmental Res Ctr E Piaggio, I-56100 Pisa, Italy
[2] Univ Pisa, Osped S Chiara, Dept Reprod & Aging, I-56100 Pisa, Italy
关键词
capsule; endoscope; endoscopic; endoscopy; magnetic; motion control; navigation; wireless;
D O I
10.1109/TBME.2007.894729
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This paper describes a technique to control the navigation of traditional wireless endoscopic capsules and reports preliminary proof-of-concept investigations. These capsules are used for noninvasive explorations of the digestive tube. At present, their motion cannot be controlled and they proceed by means of the visceral peristalsis. In order to enable motion controls, the technique proposed here adopts magnetic shells which are to be applied to available capsules, immediately before their use. The shells are used to control the capsule movement by means of external magnetic fields. This solution is readily applicable to any endoscopic capsule, avoiding internal modifications. Prototype elastic shells made of silicone elastomers mixed with magnetic particles were fabricated. They were tested with the most diffused capsule (model M2A, Given Imaging Ltd., Yoqneam, Israel), by studying the performance of the capsule/shell complex in simplified experimental conditions. Bench tests permitted to demonstrate controlled translations, rotations, and rototranslations of the capsule/shell complex within tubular structures coated with pieces of bovine tissues. The use of a new instrumentation, recently developed for cardiovascular treatments, is proposed as a potential means enabling the application of controlled magnetic fields for intrabody navigations.
引用
收藏
页码:2028 / 2036
页数:9
相关论文
共 32 条
  • [1] Capsule endoscopy is feasible in small children
    Aabakken, L
    Scholz, T
    Ostensen, AB
    Emblem, R
    Jermstad, T
    [J]. ENDOSCOPY, 2003, 35 (09) : 798 - 798
  • [2] Wireless-capsule diagnostic endoscopy for recurrent small-bowel bleeding.
    Appleyard, M
    Glukhovsky, A
    Swain, P
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (03) : 232 - 233
  • [3] A randomized trial comparing wireless capsule endoscopy with push enteroscopy for the detection of small-bowel lesions
    Appleyard, M
    Fireman, Z
    Glukhovsky, A
    Jacob, H
    Shreiver, R
    Kadirkamanathan, S
    Lavy, A
    Lewkowicz, S
    Scapa, E
    Shofti, R
    Swain, P
    Zaretsky, A
    [J]. GASTROENTEROLOGY, 2000, 119 (06) : 1431 - 1438
  • [4] Video capsule endoscopy for evaluating obscure gastrointestinal bleeding and suspected small-bowel pathology
    Bresci, G
    Parisi, G
    Bertoni, M
    Emanuele, T
    Capria, A
    [J]. JOURNAL OF GASTROENTEROLOGY, 2004, 39 (08) : 803 - 804
  • [5] BRODSKY LM, 2003, ISSUES EMERG HLTH TE, V53, P1
  • [6] CARPI F, 2005, Patent No. 2005000045
  • [7] Capsule endoscopy and Crohn's disease
    Cave, D
    [J]. GASTROINTESTINAL ENDOSCOPY, 2005, 61 (02) : 262 - 263
  • [8] Capsule endoscopy in real life: a four-centre experience of 160 consecutive patients in Israel
    Fireman, Z
    Eliakim, R
    Adler, S
    Scapa, E
    [J]. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2004, 16 (09) : 927 - 931
  • [9] Fireman Z, 2002, ISR MED ASSOC J, V4, P717
  • [10] Diagnosing small bowel Crohn's disease with wireless capsule endoscopy
    Fireman, Z
    Mahajna, E
    Broide, E
    Shapiro, M
    Fich, L
    Sternberg, A
    Kopelman, Y
    Scapa, E
    [J]. GUT, 2003, 52 (03) : 390 - 392