Symptoms, complications and management of long COVID: a review

被引:561
作者
Aiyegbusi, Olalekan Lee [1 ,2 ,3 ,4 ,5 ]
Hughes, Sarah E. [1 ,2 ,3 ]
Turner, Grace [1 ,2 ]
Rivera, Samantha Cruz [1 ,2 ,4 ]
McMullan, Christel [1 ,2 ]
Chandan, Joht Singh [1 ]
Haroon, Shamil [1 ]
Price, Gary [2 ]
Davies, Elin Haf [6 ]
Nirantharakumar, Krishnarajah [1 ,7 ]
Sapey, Elizabeth [8 ,9 ]
Calvert, Melanie J. [1 ,2 ,3 ,4 ,5 ,10 ]
机构
[1] Univ Birmingham, Inst Appl Hlth Res, Birmingham, W Midlands, England
[2] Univ Birmingham, Ctr Patient Reported Outcomes Res, Inst Appl Hlth Res, Birmingham, W Midlands, England
[3] Natl Inst Hlth Res NIHR, Appl Res Ctr West Midlands, Birmingham, W Midlands, England
[4] Univ Birmingham, Birmingham Hlth Partners Ctr Regulatory Sci & Inn, Birmingham, W Midlands, England
[5] Univ Birmingham, NIHR Birmingham Biomed Res Ctr, NIHR Surg Reconstruct & Microbiol Res Ctr, Birmingham, W Midlands, England
[6] Aparito Ltd, Wrexham, Wales
[7] Midlands Hlth Data Res UK, Birmingham, W Midlands, England
[8] Univ Birmingham, Inst Inflammat & Ageing, Birmingham Acute Care Res Grp, Birmingham, W Midlands, England
[9] Univ Hosp Birmingham NHS Fdn Trust, Acute Med, Birmingham, W Midlands, England
[10] Hlth Data Res UK, London, England
基金
美国国家卫生研究院; 英国科研创新办公室; 英国医学研究理事会;
关键词
epidemiology; health service research; infectious diseases; public health; respiratory medicine; COVID-19; long COVID; post-COVID-19; syndrome; persistent COVID-19 symptoms; ACUTE RESPIRATORY SYNDROME; RECOVERY; OUTCOMES;
D O I
10.1177/01410768211032850
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Globally, there are now over 160 million confirmed cases of COVID-19 and more than 3 million deaths. While the majority of infected individuals recover, a significant proportion continue to experience symptoms and complications after their acute illness. Patients with 'long COVID' experience a wide range of physical and mental/psychological symptoms. Pooled prevalence data showed the 10 most prevalent reported symptoms were fatigue, shortness of breath, muscle pain, joint pain, headache, cough, chest pain, altered smell, altered taste and diarrhoea. Other common symptoms were cognitive impairment, memory loss, anxiety and sleep disorders. Beyond symptoms and complications, people with long COVID often reported impaired quality of life, mental health and employment issues. These individuals may require multidisciplinary care involving the long-term monitoring of symptoms, to identify potential complications, physical rehabilitation, mental health and social services support. Resilient healthcare systems are needed to ensure efficient and effective responses to future health challenges.
引用
收藏
页码:428 / 442
页数:15
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