Arylsilanes: Application to Gold-Catalyzed Oxyarylation of Alkenes

被引：123

作者：

Ball, Liam T. ^{[1
]}

Green, Michael ^{[1
]}

Lloyd-Jones, Guy C. ^{[1
]}

Russell, Christopher A. ^{[1
]}

机构：

[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 21期

基金：

英国工程与自然科学研究理事会;

关键词：

HETEROGENEOUS CATALYSTS; COUPLING REACTIONS; COMPLEXES; ARYL; GOLD(III); HALIDES; AU(III);

D O I：

10.1021/ol1019162

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Arylsilanes are efficient reagents for the gold-catalyzed oxyarylation of alkenes (21 examples, up to 85% isolated yield). Using commercially available Ph3PAuCl and readily prepared, benign arylsilanes, these two- and three-component reactions proceed smoothly in air. The oxidant, Selectfluor, not only facilitates entry to the Au(I/III) manifold but also provides a fluoride anion for silane activation, thereby avoiding the need for addition of a stoichiometric base.

引用

页码：4724 / 4727

页数：4

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