HENOCH-SCHONLEIN PURPURA - A REVIEW

被引：0

作者：

Sinclair, Paul ^{[1
,2
]}

机构：

[1] Red Cross War Mem Childrens Hosp, Cape Town, South Africa

[2] Vincent Palotti Hosp, Cape Town, South Africa

来源：

CURRENT ALLERGY & CLINICAL IMMUNOLOGY | 2010年 / 23卷 / 03期

关键词：

THERAPY; NEPHRITIS;

D O I：

暂无

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Henoch-Schonlein purpura (HSP), the commonest childhood vasculitis, is typified by skin, joint, gastrointestinal tract and renal involvement. It shows peak incidence between the ages of 4 and 6 years and has a recurrence rate of 30%. Investigations are useful in differentiating HSP from other vasculitides but the diagnosis is clinical. Renal damage via an immune complex glomerulonephritis is the most serious long-term complication and warrants the greatest attention from clinicians: to establish who requires long-term follow-up, renal biopsy and immunosuppressive therapy. Immunosuppressive regimens are varied, and local experience with corticosteroids and azathioprine, as well as reported studies, is discussed in more detail.

引用

页码：116 / 120

页数：5

共 10 条

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