Electrochemical detection of NADH and dopamine in flow analysis based on tetraruthenated porphyrin modified electrodes

被引：64

作者：

Angnes, L ^{[1
]}

Azevedo, CMN ^{[1
]}

Araki, K ^{[1
]}

Toma, HE ^{[1
]}

机构：

[1] UNIV SAO PAULO,INST QUIM,BR-05599970 SAO PAULO,BRAZIL

来源：

ANALYTICA CHIMICA ACTA | 1996年 / 329卷 / 1-2期

基金：

巴西圣保罗研究基金会;

关键词：

flow system; biosensors; chemically modified electrodes; NADH detection; dopamine detection; ruthenium porphyrin;

D O I：

10.1016/0003-2670(96)00157-2

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Modified electrodes with molecular films of a tetraruthenated cobalt-porphyrin complex have been employed in the amperometric detection of NADH and dopamine. The electrochemical oxidation of these bioanalytes can be monitored at the onset of the Ru-III/II redox wave (E degrees = 0.70 V vs Ag/AgCl), exhibiting a very sharp peak consistent with a rapid and efficient electron transfer process. Because of the rectifying properties of the molecular films, a high selectivity for reduced species has been observed in scanning measurements. Very good signal to noise ratios have been obtained in flow analysis, ensuring a detection limit in the ppb range, for NADH and dopamine.

引用

页码：91 / 95

页数：5

共 25 条

[1] ELECTROCHEMISTRY OF A TETRARUTHENATED COBALT PORPHYRIN AND ITS USE IN MODIFIED ELECTRODES AS SENSORS OF REDUCING ANALYTES [J].