Poorly Enhanced Areas of Pancreatic Adenocarcinomas on Late-Phase Dynamic Computed Tomography Comparison With Pathological Findings

被引:27
|
作者
Hattori, Yuki [1 ]
Gabata, Toshifumi [1 ]
Zen, Yoh [2 ]
Mochizuki, Kentaro [1 ]
Kitagawa, Hirohisa [3 ]
Matsui, Osamu [1 ]
机构
[1] Kanazawa Univ, Dept Radiol, Grad Sch Med Sci, Kanazawa, Ishikawa 9208641, Japan
[2] Kanazawa Univ, Div Pathol, Grad Sch Med Sci, Kanazawa, Ishikawa 9208641, Japan
[3] Kanazawa Univ, Dept Surg Gastroenterol, Grad Sch Med Sci, Kanazawa, Ishikawa 9208641, Japan
关键词
pancreatic ductal carcinoma; computed tomography; contrast media; magnetic resonance imaging; cyst; necrosis; DUCTAL ADENOCARCINOMA; CYSTIC FEATURES; HELICAL CT; CARCINOMA; LESIONS; CANCER;
D O I
10.1097/MPA.0b013e3181dbc583
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Objectives: The aim of the study was to retrospectively compare image findings of poorly enhanced areas (PEAs) of pancreatic adenocarcinomas that show almost no enhancement or obviously hypoattenuating area relative to the surrounding carcinoma on late-phase dynamic computed tomography (CT) with pathological findings. Methods: Thirty-nine patients with pancreatic adenocarcinoma underwent dynamic CT and surgery. Poorly enhanced areas were classified according to their size, attenuation value, position, and border on CT imaging and signal intensity on magnetic resonance imaging. Results: Of the 33 PEAs, 12 showed neoplastic duct-like structure that contained both large tumor gland and dilated pancreatic duct with atypia, 11 showed necrosis, 4 showed retention cyst, 2 showed dilated pancreatic duct without atypia or with limited invasion, 1 showed mucin, and 3 showed no remarkable differences in characteristics compared with surrounding tissue. Neoplastic duct-like structures tended to be well defined (P < 0.01). Necrotic portions tended to show a high attenuation value (P < 0.01) and central position (P < 0.01) and were ill defined (P < 0.01). Retention cysts tended to show a peripheral position (P < 0.01). Conclusions: Poorly enhanced areas corresponded to cystic, necrotic, and mucinous components. Image findings demonstrated these characteristics. Necrotic component can be visualized and distinguished with other components and can be a prognostic factor.
引用
收藏
页码:1263 / 1270
页数:8
相关论文
共 44 条
  • [1] Pancreatic neuroendocrine tumors containing areas of iso- or hypoattenuation in dynamic contrast-enhanced computed tomography: Spectrum of imaging findings and pathological grading
    Hyodo, Ryota
    Suzuki, Kojiro
    Ogawa, Hiroshi
    Komada, Tomohiro
    Naganawa, Shinji
    EUROPEAN JOURNAL OF RADIOLOGY, 2015, 84 (11) : 2103 - 2109
  • [2] Dynamic Perfusion Computed Tomography and Apparent Diffusion Coefficient as Potential Markers for Poorly Differentiated Pancreatic Adenocarcinoma
    Zaboriene, Inga
    Zviniene, Kristina
    Lukosevicius, Saulius
    Ignatavicius, Povilas
    Barauskas, Giedrius
    DIGESTIVE SURGERY, 2021, 38 (02) : 128 - 135
  • [3] Evaluation of the characteristics of hepatic focal nodular hyperplasia: correlation between dynamic contrast-enhanced multislice computed tomography and pathological findings
    Zhang, Hai-Tao
    Gao, Xin-Yi
    Xu, Qin-Sha
    Chen, Yu-Tang
    Song, Yu-Piao
    Yao, Zhen-Wei
    ONCOTARGETS AND THERAPY, 2016, 9 : 5217 - 5224
  • [4] Dynamic computed tomography is useful for prediction of pathological grade in pancreatic neuroendocrine neoplasm
    Horiguchi, Shigeru
    Kato, Hironari
    Shiraha, Hidenori
    Tsutsumi, Koichiro
    Yamamoto, Naoki
    Matsumoto, Kazuyuki
    Tomoda, Takeshi
    Uchida, Daisuke
    Akimoto, Yutaka
    Mizukawa, Syou
    Tanaka, Takehiro
    Ichimura, Koichi
    Takaki, Akinobu
    Yagi, Takahito
    Okada, Hiroyuki
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2017, 32 (04) : 925 - 931
  • [5] Computed tomography of pancreatic adenocarcinoma: Comparison of tumor size measured by dynamic computed tomography and histopathologic examination
    Furukawa, H
    Takayasu, K
    Mukai, K
    Inoue, K
    Kosuge, T
    Ushio, K
    PANCREAS, 1996, 13 (03) : 231 - 235
  • [6] Optimized scan delay for late hepatic arterial or pancreatic parenchymal phase in dynamic contrast-enhanced computed tomography with bolus-tracking method
    Noda, Yoshifumi
    Kawai, Nobuyuki
    Ishihara, Takuma
    Tsuboi, Yoshiki
    Kaga, Tetsuro
    Miyoshi, Toshiharu
    Hyodo, Fuminori
    Matsuo, Masayuki
    BRITISH JOURNAL OF RADIOLOGY, 2021, 94 (1122)
  • [7] Differentiation between non-hypervascular pancreatic neuroendocrine tumour and pancreatic ductal adenocarcinoma on dynamic computed tomography and non-enhanced magnetic resonance imaging
    Ohki, Kazuyoshi
    Igarashi, Takao
    Ashida, Hirokazu
    Shiraishi, Megumi
    Nozawa, Yosuke
    Ojiri, Hiroya
    POLISH JOURNAL OF RADIOLOGY, 2019, 84 : E153 - E161
  • [8] COMPARISON BETWEEN COMPUTED-TOMOGRAPHY AND MAGNETIC-RESONANCE DATA AND PATHOLOGICAL FINDINGS IN SUBSTERNAL GOITERS
    BELARDINELLI, L
    GUALDI, G
    CERONI, L
    GUADALAXARA, A
    POLETTINI, E
    PAPPALARDO, G
    INTERNATIONAL SURGERY, 1995, 80 (01) : 65 - 69
  • [9] Pancreatic neuroendocrine tumors: Correlation between the contrast-enhanced computed tomography features and the pathological tumor grade
    Takumi, Koji
    Fukukura, Yoshihiko
    Higashi, Michiyo
    Ideue, Junnichi
    Umanodan, Tomokazu
    Hakamada, Hiroto
    Kanetsuki, Ichiro
    Yoshiura, Takashi
    EUROPEAN JOURNAL OF RADIOLOGY, 2015, 84 (08) : 1436 - 1443
  • [10] Multi-Phase, Contrast-Enhanced Computed Tomography-Based Radiomic Prognostic Marker of Non-Metastatic Pancreatic Ductal Adenocarcinoma
    Shin, Dong Woo
    Park, Jaewon
    Lee, Jong-Chan
    Kim, Jaihwan
    Kim, Young Hoon
    Hwang, Jin-Hyeok
    CANCERS, 2022, 14 (10)