Resources and Biological Activities of Natural Polyphenols

被引:619
作者
Li, An-Na [1 ]
Li, Sha [1 ]
Zhang, Yu-Jie [1 ]
Xu, Xiang-Rong [2 ]
Chen, Yu-Ming [1 ]
Li, Hua-Bin [1 ]
机构
[1] Sun Yat Sen Univ, Sch Publ Hlth, Guangdong Prov Key Lab Food Nutr & Hlth, Guangzhou 510080, Guangdong, Peoples R China
[2] Chinese Acad Sci, Key Lab Trop Marine Bioresources & Ecol, South China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
polyphenols; antioxidant; cardioprotection; anticancer; anti-inflammation; antimicrobial; bioavailability; TOTAL PHENOLIC CONTENTS; GRAPE SEED EXTRACT; DIFFERENT COOKING METHODS; CENTRAL-NERVOUS-SYSTEM; GREEN TEA POLYPHENOLS; NF-KAPPA-B; ANTIOXIDANT CAPACITY; DIETARY POLYPHENOLS; RED WINE; OLIVE OIL;
D O I
10.3390/nu6126020
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The oxidative stress imposed by reactive oxygen species (ROS) plays an important role in many chronic and degenerative diseases. As an important category of phytochemicals, phenolic compounds universally exist in plants, and have been considered to have high antioxidant ability and free radical scavenging capacity, with the mechanism of inhibiting the enzymes responsible for ROS production and reducing highly oxidized ROS. Therefore, phenolic compounds have attracted increasing attention as potential agents for preventing and treating many oxidative stress-related diseases, such as cardiovascular diseases, cancer, ageing, diabetes mellitus and neurodegenerative diseases. This review summarizes current knowledge of natural polyphenols, including resource, bioactivities, bioavailability and potential toxicity.
引用
收藏
页码:6020 / 6047
页数:28
相关论文
共 149 条
  • [21] Resveratrol stimulates AMP kinase activity in neurons
    Dasgupta, Biplab
    Milbrandt, Jeffrey
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (17) : 7217 - 7222
  • [22] Anticancer Activity of Green Tea Polyphenols in Prostate Gland
    Davalli, Pierpaola
    Rizzi, Federica
    Caporali, Andrea
    Pellacani, Davide
    Davoli, Serena
    Bettuzzi, Saverio
    Brausi, Maurizio
    D'Arca, Domenico
    [J]. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2012, 2012
  • [23] Antioxidant capacities and total phenolic contents of 56 vegetables
    Deng, Gui-Fang
    Lin, Xi
    Xu, Xiang-Rong
    Gao, Li-Li
    Xie, Jie-Feng
    Li, Hua-Bin
    [J]. JOURNAL OF FUNCTIONAL FOODS, 2013, 5 (01) : 260 - 266
  • [24] Phenolic Compounds and Bioactivities of Pigmented Rice
    Deng, Gui-Fang
    Xu, Xiang-Rong
    Zhang, Yuan
    Li, Dan
    Gan, Ren-You
    Li, Hua-Bin
    [J]. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2013, 53 (03) : 296 - 306
  • [25] Potential of Fruit Wastes as Natural Resources of Bioactive Compounds
    Deng, Gui-Fang
    Shen, Chen
    Xu, Xiang-Rong
    Kuang, Ru-Dan
    Guo, Ya-Jun
    Zeng, Li-Shan
    Gao, Li-Li
    Lin, Xi
    Xie, Jie-Feng
    Xia, En-Qin
    Li, Sha
    Wu, Shan
    Chen, Feng
    Ling, Wen-Hua
    Li, Hua-Bin
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2012, 13 (07): : 8308 - 8323
  • [26] Protection of Dietary Polyphenols against Oral Cancer
    Ding, Yijian
    Yao, Hua
    Yao, Yanan
    Fai, Leonard Yenwong
    Zhang, Zhuo
    [J]. NUTRIENTS, 2013, 5 (06) : 2173 - 2191
  • [27] Regulation of Hypoxia-Inducible Factor 2α Signaling by the Stress-Responsive Deacetylase Sirtuin 1
    Dioum, Elhadji M.
    Chen, Rui
    Alexander, Matthew S.
    Zhang, Quiyang
    Hogg, Richard T.
    Gerard, Robert D.
    Garcia, Joseph A.
    [J]. SCIENCE, 2009, 324 (5932) : 1289 - 1293
  • [28] Quince (Cydonia oblonga Miller) peel polyphenols modulate LPS-induced inflammation in human THP-1-derived macrophages through NF-κB, p38MAPK and Akt inhibition
    Essafi-Benkhadir, Khadija
    Refai, Amira
    Riahi, Ichrak
    Fattouch, Sami
    Karoui, Habib
    Essafi, Makram
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2012, 418 (01) : 180 - 185
  • [29] Reversing β-lactam antibiotic resistance of Staphylococcus aureus with galangin from Alpinia officinarum Hance and synergism with ceftazidime
    Eumkeb, Griangsak
    Sakdarat, Santi
    Siriwong, Supatcharee
    [J]. PHYTOMEDICINE, 2010, 18 (01) : 40 - 45
  • [30] Polyphenol content and antioxidant capacity in organic and conventional plant foods
    Faller, A. L. K.
    Fialho, E.
    [J]. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 2010, 23 (06) : 561 - 568