Construction and evolution of antibody-phage libraries by DNA shuffling

被引：80
作者：
Crameri, A
Cwirla, S
Stemmer, WPC
机构：
来源：
NATURE MEDICINE | 1996年 / 2卷 / 01期
关键词：
D O I：
10.1038/nm0196-100
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：100 / 102
页数：3
相关论文
共 11 条
[1]  
CRAMERI A, 1995, BIOTECHNIQUES, V18, P194
[2]   ISOLATION OF HIGH-AFFINITY HUMAN-ANTIBODIES DIRECTLY FROM LARGE SYNTHETIC REPERTOIRES [J].
GRIFFITHS, AD ;
WILLIAMS, SC ;
HARTLEY, O ;
TOMLINSON, IM ;
WATERHOUSE, P ;
CROSBY, WL ;
KONTERMANN, RE ;
JONES, PT ;
LOW, NM ;
ALLISON, TJ ;
PROSPERO, TD ;
HOOGENBOOM, HR ;
NISSIM, A ;
COX, JPL ;
HARRISON, JL ;
ZACCOLO, M ;
GHERARDI, E ;
WINTER, G .
EMBO JOURNAL, 1994, 13 (14) :3245-3260
[3]   SELECTION OF PHAGE ANTIBODIES BY BINDING-AFFINITY - MIMICKING AFFINITY MATURATION [J].
HAWKINS, RE ;
RUSSELL, SJ ;
WINTER, G .
JOURNAL OF MOLECULAR BIOLOGY, 1992, 226 (03) :889-896
[4]   DIABODIES - SMALL BIVALENT AND BISPECIFIC ANTIBODY FRAGMENTS [J].
HOLLIGER, P ;
PROSPERO, T ;
WINTER, G .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (14) :6444-6448
[5]  
KABAT EA, 1991, NIH913242 PUBL
[6]   APPLIED EVOLUTION - THE PROGENY OF SEXUAL PCR [J].
SMITH, GP .
NATURE, 1994, 370 (6488) :324-325
[7]   RAPID EVOLUTION OF A PROTEIN IN-VITRO BY DNA SHUFFLING [J].
STEMMER, WPC .
NATURE, 1994, 370 (6488) :389-391
[8]   DNA SHUFFLING BY RANDOM FRAGMENTATION AND REASSEMBLY - IN-VITRO RECOMBINATION FOR MOLECULAR EVOLUTION [J].
STEMMER, WPC .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (22) :10747-10751
[9]  
STEMMER WPC, 1995, BIO-TECHNOL, V13, P549, DOI 10.1038/nbt0695-549
[10]  
STEMMER WPC, IN PRESS SCIENCE
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