Nanomechanics of individual amyloid fibrils using atomic force microscopy

被引：8
|
作者：
Zhou XingFei [1 ]
Cui ChengYi [1 ]
Zhang JinHai [1 ]
Liu JianHua [1 ]
Liu JingSong [1 ]
机构：
[1] Ningbo Univ, Coll Sci, Nanomat Lab, Ningbo 315211, Zhejiang, Peoples R China
来源：
CHINESE SCIENCE BULLETIN | 2010年 / 55卷 / 16期
基金：
中国国家自然科学基金;
关键词：
amyloid fibrils; nanoindentation; AFM; elastic modulus; GLUCAGON FIBRILLATION; RADIAL COMPRESSION; ELASTIC PROPERTIES; POLYMORPHISM; NANOTUBES;
D O I：
10.1007/s11434-010-3201-9
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Compression elasticity of glucagon amyloid fibrils in the transverse direction was investigated by a nanoindentation approach based on atomic force microscopy (AFM). With force-volume mapping, we obtained the correlations between radially applied force and compression of amyloid fibrils, from which the radial compressive elasticity can be deduced. The estimated elastic modulus at three typical locations of fibrils varied from (0.72 +/- 0.80) GPa to (1.26 +/- 0.62) GPa under small external forces, implying the structural heterogeneity of different fibrils.
引用
收藏
页码：1608 / 1612
页数：5
相关论文
共 50 条
  • [1] Nanomechanics of individual amyloid fibrils using atomic force microscopy
    ZHOU XingFei
    Science Bulletin, 2010, (16) : 1608 - 1612
  • [2] Nanomechanics of individual amyloid fibrils using atomic force microscopy
    ZHOU XingFeiCUI ChengYiZHANG JinHaiLIU JianHua LIU JingSong Nanomaterials LaboratoryCollege of SciencesNingbo UniversityNingbo China
    Chinese Science Bulletin, 2010, 55 (16) : 1608 - 1612
  • [3] Ultrastructural organization of amyloid fibrils by atomic force microscopy
    Chamberlain, AK
    MacPhee, CE
    Zurdo, J
    Morozova-Roche, LA
    Hill, HAO
    Dobson, CM
    Davis, JJ
    BIOPHYSICAL JOURNAL, 2000, 79 (06) : 3282 - 3293
  • [4] Study of amyloid fibrils via atomic force microscopy
    Adamcik, Jozef
    Mezzenga, Raffaele
    CURRENT OPINION IN COLLOID & INTERFACE SCIENCE, 2012, 17 (06) : 369 - 376
  • [5] Development of quantitative analysis methods of amyloid fibrils using atomic force microscopy
    Schifone, Christine
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 250
  • [6] Watching amyloid fibrils grow by atomic force microscopy (AFM).
    Goldsbury, C
    Kistler, J
    Aebi, U
    Arvinte, T
    Cooper, G
    MOLECULAR BIOLOGY OF THE CELL, 1998, 9 : 455A - 455A
  • [7] Nanomechanics Using Atomic Force Microscopy and Its Practical Examples
    Nakajima K.
    Hanai M.
    Ito M.
    Liang X.
    Mogi K.
    Journal of Fiber Science and Technology, 2022, 78 (02) : P83 - P89
  • [8] Nanomechanics Using Atomic Force Microscopy and Its Practical Examples
    Nakajima, Ken
    Ito, Makiko
    Hanai, Mari
    Liang, Xiaobin
    Mogi, Kaede
    SEN-I GAKKAISHI, 2022, 78 (02) : 83 - 89
  • [9] Bottom Effect in Atomic Force Microscopy Nanomechanics
    Chiodini, Stefano
    Ruiz-Rincon, Silvia
    Garcia, Pablo D.
    Martin, Santiago
    Kettelhoit, Katharina
    Armenia, Ilaria
    Werz, Daniel B.
    Cea, Pilar
    SMALL, 2020, 16 (35)
  • [10] Probing the nanomechanics of cartilage with atomic force microscopy
    Day, C
    PHYSICS TODAY, 2002, 55 (09) : 21 - 23
12345