A Novel Method for the Synthesis of (1,8-Dioxo-2,3,4,5,6,7,8,9-octahydro-1H-xanthen-9-yl)acetic Acids on Solid Phase

被引：6

作者：

Cravero, Raquel M. ^{[1
]}

Luna, Liliana E. ^{[1
]}

Barboza, Andrea V. ^{[1
]}

机构：

[1] Univ Nacl Rosario Suipacha 531, Fac Ciencias Bioquim & Farmaceut, IQUIR Inst Quim Rosario, Rosario, Santa Fe, Argentina

来源：

SYNTHESIS-STUTTGART | 2011年 / 24期

关键词：

polycycles; tandem reactions; cycloadditions; Michael addition; solid-phase synthesis; SUPPORTED SYNTHESIS; DERIVATIVES; THIOACETALIZATION; XANTHONES; EFFICIENT;

D O I：

10.1055/s-0031-1289602

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report the first solid-phase synthesis of (1,8-dioxo-2,3,4,5,6,7,8,9-octahydro-1H-xanthen-9-yl)acetic acids via a tandem Michael-Michael cyclization with resin-bound propiolic acid as Michael acceptor and cyclohexanediones.

引用

页码：4027 / 4032

页数：6